Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Multicenter Cohort Study) III

Conditions

Aortic Dissection

Keywords

Aortic Dissection, Inflammatory Response

Brief summary

Anatomopathological classifications have been well identified in aortic dissection with important therapeutic implications. The authors evaluated the inflammatory response in patients with aortic dissection (AD) and assessed the presence of distinct inflammatory subphenotypes within this disease.

Liu H, Zhang YY, Ding XH, Qian SC, Sun MY, Hamzah AW, Gao YN, Shao YF, Li HY, Wang K, Ni BQ, Zhang HJ, Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (5A) Investigators.

2023-04-258 citations

10.1016/j.athoracsur.2023.04.019

Laboratory signatures differentiate the tolerance to hypothermic circulatory arrest in acute type A aortic dissection surgery

Hong Liu, Si-chong Qian, Lu Han, Zhiqiang Dong, Yongfeng Shao et al. (8 authors)

Interactive Cardiovascular and Thoracic Surgery2022-10-223 citations

10.1093/icvts/ivac267

Prognostic Impact of Systemic Coagulation-Inflammation Index in Acute Type A Aortic Dissection Surgery

Hong Liu, Si-chong Qian, Yongfeng Shao, Haiyang Li, Hongjia Zhang

JACC Asia2022-10-0431 citations

10.1016/j.jacasi.2022.06.007

A Novel Inflammation-Based Risk Score Predicts Mortality in Acute Type A Aortic Dissection Surgery: The Additive Anti-inflammatory Action for Aortopathy and Arteriopathy Score

Hong Liu, Si-chong Qian, Yingyuan Zhang, Ying Wu, Liang Hong et al. (16 authors)

Mayo Clinic Proceedings Innovations Quality & Outcomes2022-09-2514 citations

10.1016/j.mayocpiqo.2022.08.005

Anti-Inflammatory Effect of Ulinastatin on the Association Between Inflammatory Phenotypes in Acute Type A Aortic Dissection

Hong Liu, Si-chong Qian, Yongfeng Shao, Haiyang Li

Journal of Inflammation Research2022-06-0114 citations

10.2147/jir.s369703

Interventions

BIOLOGICALinflammatory response

laboratory data (leukocyte, neutrophils, monocyte, lymphocytes, platelet, fibrinogen, D-dimer, neutrophils-lymphocyte ratio, platelet-lymphocyte ratio, lymphocyte-monocyte ratio)

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

No

Inclusion criteria

* acute type Aortic dissection;

Exclusion criteria

* Iatrogenic aortic dissection OR traumatic aortic dissection * Patients with hematological diseases, infectious diseases, malignant tumors, immune system diseases, or severe liver diseases. * Preoperative use of mechanical ventilation, blood transfusion, renal replacement therapy, extracorporeal membrane oxygenation, or intra-aortic balloon pump during the current admission.

Design outcomes

Primary

Measure	Time frame	Description
30-day mortality	30 days after surgery	any cause death within 30 days of surgery

Secondary

Measure	Time frame	Description
ICU mortality	7 days after surgery	any cause death within ICU

Countries

China

Outcome results

None listed