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Efficacy Trial of Life Simulation Game to Routinize Adolescent HIV Testing

Efficacy Trial of Life Simulation Game to Routinize Adolescent HIV Testing

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04917575
Enrollment
300
Registered
2021-06-08
Start date
2021-06-24
Completion date
2024-10-31
Last updated
2025-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hiv

Keywords

HIV prevention, HIV testing, mHealth, Pre-exposure prophylaxis (PrEP), adolescents, interactive technology

Brief summary

This study will aim to assess the acceptability, usability and efficacy of using state-of-the-art video game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24. AYA often lack awareness of their personal risk of contracting HIV and where to go for testing and care. This lack of awareness has contributed to poor uptake of HIV testing among AYA despite engagement in high risk behaviors. The goal of this project is to harness this strong motivation to play games to increase HIV testing. Previous games for behavior change have yielded early success for increasing target behaviors among their sample populations, yet research on increasing HIV testing among AYA through gaming has been limited. This intervention builds on prior formative work and is designed to offer AYA personally-tailored risk messages and supports their accessibility to HIV testing and prevention services through an innovative gaming approach that is sharable over social media with in-game rewards for sharing the game with peers. The specific aim of this study is to determine the efficacy of a life-simulation game in changing HIV testing, knowledge, and risk behaviors among AYA at risk for HIV.

Interventions

An enhanced life-simulation prototype of a playable interactive game to increase HIV testing.

OTHERMobile Application

A mobile application that will include basic information on HIV basics (e.g., routes of transmission, data on the epidemiology of HIV among youth), prevention information, and information on HIV testing and PrEP, as well as a link to the HIV risk estimator, and HIV testing and PrEP locators.

Sponsors

Media Rez
CollaboratorUNKNOWN
George Washington University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
13 Years to 24 Years
Healthy volunteers
Yes

Inclusion criteria

* age 13-24 * self-reported HIV negative or unknown status * self-reported ever sexually active * resident of the DC metropolitan region which includes the District of Columbia, Maryland and Virginia for at least the next 6 months * Is able to provide informed consent or assent * able to complete all study procedures in English * has own mobile phones and be willing to use them for the study.

Design outcomes

Primary

MeasureTime frameDescription
HIV testingprior 6 monthsSelf-reported HIV testing in the past 6 months

Secondary

MeasureTime frameDescription
HIV knowledgebaseline, 1, 3, 6 months18-item scale
HIV risk perception and behaviorsbaseline, 1, 3, 6 months8-item scale and perceived likelihood of getting infected (0-100%)
Knowledge of PrEPbaseline, 1, 3, 6 monthsHas participant heard of PrEP at specified time period
CDC risk estimator scoresbaseline, 1, 3, 6 months
Frequency of game use1, 3, 6 months
Intent to test for HIVbaseline, 1, 3, 6 monthsIntent to test will be assessed using a validated 6-point Likert scale
PrEP use/uptakebaseline, 1, 3, 6 monthsbeen prescribed/taken PrEP
PrEP locator usebaseline, 1, 3, 6 monthsNumber of linkages to PrEP locator
Duration of game use1, 3, 6 months
Reasons for continued or discontinued use of game1, 3, 6 months
HIV locator usebaseline, 1, 3, 6 monthsNumber of linkage to HIV testing locator
PrEP screeningbaseline, 1, 3, 6 monthsever been screened for PrEP eligibility

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 15, 2026