SARS-CoV2 Infection
Conditions
Brief summary
Primary purpose: To investigate the effect of propolis, a food supplement product, on healing parameters in patients with COVID 19. Secondary purpose: To provide a new supportive treatment in Covid 19 treatment. In the present study to examine the effect of the use of propolis on healing parameters (laboratory and imaging) in patients with COVID 19; Propolis, which has antiviral properties, has also been used in humans in the COVID19 pandemic as of 2020. However, in these studies, an alcohol-soluble extract of propolis was used. Despite the disadvantages of its use in alcohol, it is clear that water and olive oil extracts of Propolis are safer for humans. Therefore, water extracts of propolis will be used in the study.
Interventions
DIETARY_SUPPLEMENTpropolis
Propolis may be blocked virus entry to cells, and some receptor binding and some cell signal molecules
Sponsors
Trabzon Kanuni Education and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
first group treated with water extracts of propolis second group treated with olive oil extracts of propolis including perga third group treated with no bee product
Eligibility
Sex/Gender
ALL
Age
18 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients over the age of 18 who do not need a ventilator who are inpatient in the Covid service * Patients under the age of 60 who do not need a ventilator who are inpatient in the Covid service
Exclusion criteria
* patients do not have oral intake * patients whose informed consent form is not approved * patients who need a ventilator * pregnant women * children
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| radiological | Change from Baseline Lung Tomography Findings(Peripheral ground-glass opacities) at one week | Lung tomography findings |
| laboratory parameters-2: ESR | Change from Baseline ESR findings at one week | ESR |
| laboratory parameters-3: CRP | Change from Baseline CRP findings at one week | CRP |
| laboratory parameters-4: D-Dimer | Change from Baseline D-Dimer findings at one week | D-Dimer |
| laboratory parameters-5: Troponin | Change from Baseline Troponin findings at one week | Troponin |
| laboratory parameters-6: sO2 | Change from Baseline sO2 findings at one week | sO2 |
| laboratory parameters-1: CBC | Change from Baseline CBC findings at one week | CBC |
Countries
Turkey (Türkiye)
Outcome results
None listed