Cirrhosis
Conditions
Brief summary
Cirrhotic patients are more vulnerable to bacterial infection, and infection is one of the most common causes of acute liver disease decompensation.
Detailed description
Cirrhotic patients are more vulnerable to bacterial infection which is a common cause of acute liver disease decompensation. The aim of this study will characterize the antimicrobial resistance and distribution of bacteria isolated from chronic hepatic patients with pulmonary infections, as well as to evaluate the antimicrobial susceptibility of bacteria isolated from sputum.
Interventions
DIAGNOSTIC_TESTSpecimen
Sputum will be collected in clean disposable containers
Sponsors
Tanta University
Mansoura University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
1\. Adults' older than 18 years with clinical evidence of liver disease
Exclusion criteria
1. Pregnancy 2. Intensive care unite stay of more than 24 hours 3. Malignancy 4. Organ transplantation 5. Acquired immune deficiency syndrome
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Isolate Identification | One day | Distribution of bacterial isolates from sputum of cirrhotic patients expressed by frequency of each isolate |
| Antimicrobial resistance | One day | Antimicrobial susceptibility testing to antibiotics determined by kirby-bauer disk diffusion |
Countries
Egypt
Contacts
Primary ContactNoha Mansour, Ph.D
Outcome results
None listed