Arthroplasty Complications
Conditions
Brief summary
The cemented femoral stem have impact on increase on systemic parameters. Evaluation of the level of histamine, C-reactive protein (CRP) and leukocytes formula, IL1b, TNF alpha, IL6 and the reflection of changes of these parameters in the intra-operative course of hip replacement.
Detailed description
Implantation of total endoprosthesis is a very common surgical procedure and is performed with and without bone cement. In most cases during cementation of the femoral component there are changes in blood pressure, SpO2, heartbeat and other vital parameters which can cause complications during surgery. Comparing the system parameters between the two groups and deriving these results will help the medical staff to be more professionally prepared to resolve possible complications.
Interventions
PROCEDUREHip Replacement
The hip replacement surgery is when a damaged hip is replaced with artificial one
Sponsors
University Clinical Centre of Kosova
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
The inclusion criteria were as follows: * All patients willing to participate who underwent cemented and uncemented THA, * With no limit on age
Exclusion criteria
The
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of systemic parameters during and after hip replacement (IL6) | The measurement of these laboratory parameters 5 minutes before and 10 minutes after surgical procedures will reflect the impact of cements in the eventual post-surgical complications, such are embolism and other complications. | Analysis of the impact of cement in different laboratory parameters such as IL6. |
| Change of systemic parameters during and after hip replacement (Leukocytes formula) | The measurement of these laboratory parameters 5 minutes before and 10 minutes after surgical procedures will reflect the impact of cements in the eventual post-surgical complications, such are embolism and other complications. | Analysis of the impact of cement in different laboratory parameters such as changes of leukocytes formula |
| Change of systemic parameters during and after hip replacement (IL1b) | The measurement of these laboratory parameters 5 minutes before and 10 minutes after surgical procedures will reflect the impact of cements in the eventual post-surgical complications, such are embolism and other complications. | Analysis of the impact of cement in different laboratory parameters such as IL1b |
| Change of systemic parameters during and after hip replacement (TNF alpha) | The measurement of these laboratory parameters 5 minutes before and 10 minutes after surgical procedures will reflect the impact of cements in the eventual post-surgical complications, such are embolism and other complications. | Analysis of the impact of cement in different laboratory parameters such are TNF alpha |
| Change of systemic parameters during and after hip replacement (Histamine) | The measurement of these laboratory parameters 5 minutes before and 10 minutes after surgical procedures will reflect the impact of cements in the eventual post-surgical complications, such are embolism and other complications. | Analysis of the impact of cement in different laboratory parameters such as histamine |
| Change of systemic parameters during and after hip replacement (CRP) | The measurement of these laboratory parameters 5 minutes before and 10 minutes after surgical procedures will reflect the impact of cements in the eventual post-surgical complications, such are embolism and other complications. | Analysis of the impact of cement in different laboratory parameters such as C-reactive protein (CRP) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Difference of changes of Leukocyte formula | The blood will be taken from patience 1 hour before and Post Operative Day One | Difference of changes of Leukocyte formula after implantation of femoral component |
| Difference of SpO2 | The changes will be measured 5 minutes before implantation and during first 10 minutes after implantation] | Difference of SpO2 after implantation of femoral component The changes will be measured by the device monitor connected to patient |
| Difference of arterial pressure | The changes will be measured 5 minutes before implantation and during first 10 minutes after implantation | Difference of arterial pressure after implantation of femoral component |
Countries
Kosovo
Contacts
Primary ContactSkender Ukaj, MD
Outcome results
None listed