Colorectal Cancer
Conditions
Keywords
Colorectal cancer, Cancer Screening, Colonoscopy, APCS, HRFQ
Brief summary
Background: The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires. However, the colorectal cancer screening technology that has been widely used at present cannot take into account sensitivity and specificity, and the tumor detection rate is low. The purpose of research: 1. Build a new type of population colorectal cancer precision screening technology program; 2. Improve the detection rate of colorectal cancer in the population by new methods (compared with the existing domestic advanced technology) by ≥20%, and improve the specificity of colorectal cancer screening by ≥15% without significantly reducing the sensitivity.
Interventions
None listed
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 74 Years
Healthy volunteers
Yes
Inclusion criteria
Age: 40-74 years old
Exclusion criteria
1. Combine severe disorders to make it unsuitable for colonoscopy 2. Combine other tumors 3. Mental and behavioral abnormalities do not cooperate with the screener 4. Researchers believe that other reasons are not suitable for enrollment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Colorectal cancer detection rate in the population | through study completion, an average of 3 years | Colorectal cancer detection rate in the population |
| Colorectal cancer screening specificity | through study completion, an average of 3 years | Colorectal cancer screening specificity |
| Colorectal cancer screening sensitivity | through study completion, an average of 3 years | Colorectal cancer screening sensitivity |
Countries
China
Contacts
Primary ContactYing Yuan
Backup ContactYanqin Huang
Outcome results
None listed