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Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma

Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04912310
Enrollment
65
Registered
2021-06-03
Start date
2020-07-13
Completion date
2021-07-31
Last updated
2021-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Angle-Closure Glaucoma

Keywords

Acute angle-closure glaucoma, Argon laser peripheral iridoplasty

Brief summary

To investigate the changes of angle structure and intraocular pressure after argon laser peripheral iridoplasty in patients with acute angle closure glaucoma patients whose intraocular pressure could not be controlled by drug therapy during the major attack period.

Detailed description

To evaluate intraocular pressure and anterior segment optical coherence tomography measurement parameters at baseline and each follow-up. Each patient was followed up for 6 weeks for 9 times. Visit 1st was baseline examination, visit 2nd was 1 hour after argon laser peripheral iridoplasty treatment, visit 3rd was 2 hours after argon laser peripheral iridoplasty treatment, visit 4th was 1 week after argon laser peripheral iridoplasty treatment, visit 5th was 2 week after argon laser peripheral iridoplasty treatment, and visit 6th was 1 month after argon laser peripheral iridoplasty treatment, visit 7th was 6 week after argon laser peripheral iridoplasty treatment.

Interventions

Argon laser peripheral iridoplasty was performed in patients with severe acute angle closure glaucoma whose intraocular pressure could not be controlled by medication

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* One eye had an acute attack, which could not be relieved by medication, and the intraocular pressure was more than 21mmhg; * The patients were 40 to 80 years old, regardless of gender; * Patients are able and willing to comply with the research guidance and may complete all visits required by the research; * Informed consent has been signed.

Exclusion criteria

* History of ocular trauma; * Any previous intraocular surgery; * Secondary glaucoma was diagnosed, including uveitis, neovascular glaucoma, glaucoma with elevated superior scleral venous pressure, lens dissolution glaucoma, glaucoma caused by lens dislocation, lens cortical glaucoma, pigmented glaucoma, etc; * The patient's history indicated that he had severe dysfunction of heart, lung, liver and kidney; * Women in pregnancy, lactation or planned pregnancy; * The researchers believe that the patient's condition may put the patient at a significant risk, may confuse the results of the study, or may significantly interfere with the patient's participation in the study.

Design outcomes

Primary

MeasureTime frameDescription
Intraocular pressure6 weeksIntraocular pressure

Countries

China

Contacts

Primary Contactkaijun wang, MD
wkj992@126.com+86 0571 87783759

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026