Peripheral Arterial Disease
Conditions
Brief summary
The goal is to compare the results observed in patients that had both an exercise oximetry and a thallium scintigraphy for lower limb claudication
Detailed description
On our routine pratice, patients suffering claudication (specifically atypical claudication or claudication of doubful vascular origin) have exercise oximetry to prove the vascular origin of pain. If still doubtful (inconsistency of pain and oximetry results) patients are referred for thallium scintigraphy. Our goal is to compare the results issued from these two test
Interventions
DIAGNOSTIC_TESTexercise oximetry
transcutaneous oxygen pressure is measured at the skin level on chest , buttocks and calves during a walking test 3.2 km\*:h 10% slope. From the test result the decrease from rest of oxygen pressure (DROP) index is calculated to estimate muscle ischemia
DIAGNOSTIC_TESTthallium scintigraphy
Muscle thallium fixation is measured immediately after a walking test 3.2 km\*:h 10% slope and at 4 hours after the test. From the test result the difference of late and early radioactivity is calculated at the buttock and calf level and normalized to total body radioactivity to estimate muscle ischemia
Sponsors
University Hospital, Angers
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Claudication suspected of arterial origin
Exclusion criteria
* missing endopoint value
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation of thallium scintigraphy to oximetry results | 1 year | The coefficient of correlation of DROP values to normalized late to early changes in radioactivity wil be calculated at the calf and buttock level |
Countries
France
Contacts
Primary Contactpierre abraham, MD; PhD
Backup ContactMarine Mauboussin
Outcome results
None listed