HIV Infections
Conditions
Keywords
HIV testing, PrEp, HIV care, Chatbot, MSM
Brief summary
In this study, the feasibility of a Chatbot in promoting HIV testing in a pilot RCT with 80 men who have sex with men in Kuala Lumpur, Malaysia will be studied. Participants will be randomized to Chatbot or treatment as usual (TAU) groups. Participants in the intervention group will receive automated personalized messages containing HIV testing-related information, motivation and skills.
Detailed description
After informed consent, participants will be randomly assigned to Chatbot or TAU groups using stratified randomization by age. Participants in TAU will receive attention-matched educational materials manually sent by the research assistant. Participants in the intervention group will receive an automated personalized question message (root-node message) from the Chabot. In each round of the interactive communication, the Chatbot will provide automated personalized messages containing HIV testing-related information, motivation and skills based on participants' answers and will continuously update over time. Participants will be observed over 180 days with responses and interactions stored on a HIPAA-compliant and protected cloud. An independent assessment of recent testing and reasons why will be sent by link to both TAU and intervention groups using a link to a Qualtrics survey housed on REDCap at baseline and after 90 and 180 days. After 180 days, the RA will send an additional REDCap survey to intervention participants to assess the feasibility of the Chabot to measure 4 key elements: acceptability, practicality, demand, and adaptation.
Interventions
BEHAVIORALChatbot messages
Automated personalized messages containing HIV testing-related information, motivation and skills
BEHAVIORALAttention-matched educational materials
Attention-matched educational materials manually sent by our research assistant. These educational materials will be retrieved from CDC and WHO websites and curated into short articles (\<200 words) and pictures. All educational materials will be screened by HIV experts from University of Malaya to ensure accuracy before being sent to participants.
Sponsors
Yale University
University of Malaya
National Institute of Allergy and Infectious Diseases (NIAID)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* cis-gender male * 18+ years; * had condomless sex with men in the past 6 months * has a smartphone * speaks Bahasa Malay or English.
Exclusion criteria
* Not able to read Malay or English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in HIV testing | 30 days, 60 days, 90 days, 120 days, 150 days, and 180 days | The efficacy of the Chatbot versus TAU with HIV testing as the primary outcome will be measured. The primacy efficacy outcome is the proportion of MSM who get tested within 180 days. This will be measured every 30 days by asking if MSM tested for HIV in the past 30 days. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recruitment rate | 180 days | The number of participants contacted divided by the number of participants who signed the consent form |
| Completion rate | 180 days | The number of participants who signed the consent form divided by the number of participants who completed the study |
| Interaction time | 180 days | The time of the interaction between participants and Chatbot |
| Interaction frequency | 180 days | The frequency of the interaction between participants and Chatbot |
Countries
Malaysia
Contacts
PRINCIPAL_INVESTIGATORJeffrey A. Wickersham, PhD
Yale University
Outcome results
None listed