Covid19
Conditions
Keywords
covid-19, danish icu, long-term follow-up
Brief summary
This study is a prospective observational cohort study of 6 and 12 months long-term outcome of Danish speaking patients with COVID-19.
Detailed description
To describe frailty, cognitive function, functional status, fatigue, mortality and the quality of life 6 and 12 months after ICU admission of the COVID-19 patients enrolled in the Danish ICU COVID-19 database. Furthermore to investigate the association between ventilator days and Clinical Frailty Score (CFS) and the MiniMoCA, respectively at 6 and 12 months after ICU admission
Interventions
None listed
Sponsors
Zealand University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* \> 18 years * enrolled in the 'Danish ICU COVID-19 database'
Exclusion criteria
* non danish speaking patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The cognitive status at 6 and 12 months after ICU admission using the validated instrument MiniMoCA | at 6 and 12 months after ICU admission | The cognitive status at 6 and 12 months after ICU admission using the validated instrument MiniMoCA. Score 0-15, score above 11 indicate normal cognitive function. Two time points to see if there is a change in the cognitive status over time. |
| The functional status at 6 and 12 months after ICU admission using the validated instrument CFS | at 6 and 12 months after ICU admission | The functional status at 6 and 12 months after ICU admission using the validated instrument CFS (score 1-9) higher levels indicate more frailty. Two time points to see if there is a change in the frailty status over time. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | Mortality 6 and 12 months after ICU admission. To see if there is a change i mortality at 6 and 12 months. |
| EQ-5D-5L score 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | EQ-5D-5L score 6 and 12 months after ICU admission. Score 5-25. low score indicate better quality of life. Two time points to see if there is a change. |
| The association between ventilator days and CFS 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | The association between ventilator days and CFS 6 and 12 months after ICU admission. Will be one analysis. |
| Lawton-Brody IADL score 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | Lawton-Brody IADL score 6 and 12 months after ICU admission. score from 0-8 for female and 0-5 for male. High score indicate high independence. Two time points to see if there is a change. |
| FAS score 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | FAS score 6 and 12 months after ICU admission. score from 10-50, high score indicate high level of fatigue. Two time points to see if there is a change. |
| Barthel ADL score 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | Barthel ADL score 6 and 12 months after ICU admission. Score 0-20, high score indicate high independence. Two time points to see if there is a change. |
| The association between ventilator days and MiniMoCA 6 and 12 months after ICU admission | at 6 and 12 months after ICU admission | The association between ventilator days and MiniMoCA 6 and 12 months after ICU admission. Will be one analysis. But need to time points to see if there is a change. |
Countries
Denmark
Outcome results
None listed