Autism, Autism Spectrum Disorder
Conditions
Keywords
digital, mobile, autism
Brief summary
The investigators will test the feasibility and preliminary efficacy of a Mobile game system meant to generate valuable data for measuring progress and building novel artificial intelligence models while delivering impactful education for and treatment of children with developmental delays such as autism. Investigators will enroll children with autism aged 2-8 years old and their neurotypical sibling or an unrelated neurotypical control (aged 2-8 years old).
Interventions
OTHERMobile Game System for Potential Treatment of Developmental Delays
Mobile game system meant to generate valuable data for measuring progress and building novel artificial intelligence models while delivering impactful education for and treatment of children with developmental delays such as autism.
Sponsors
Stanford University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Intervention model description
The investigators will use parallel assignment to compare the device feasibility across children with autism and neurotypical children, who will serve as controls.
Eligibility
Sex/Gender
ALL
Age
2 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
1. Parent or primary caregiver over 18 of a child with autism, we will enrich for children between the ages of 2 and 8 years old. 2. Autism diagnosis confirmed by a screener such as the Mobile Autism Risk Assessment (MARA) and or similar published tools.
Exclusion criteria
(1) Physical, intellectual, language related, or environmental limitations that prevent the ability for the family to play the game as intended.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in parent reported socialization subscale scores of the Vineland Adaptive Behavior Scales,2nd Edition (VABS-2) from baseline to week 12 Vineland Adaptive Behavior Scales, 2d edition (VABS-2) Socialization subscale of the Parent/Caregiver | Baseline (Week 0), Week 12 | The socialization subscale is up to 113 items, where raw scores are converted to Intelligence Quotient (IQ) type standard scores--v-scale scores (M=15, SD=3) where scores range from 1 to 24, and factor in age equivalents, growth scale values, and higher scores indicate better adaptive functioning. |
| Mobile Application Usage-Total games started. | Week 12 | App usage data by participants (children) comprised of total number of MojiMatch plus Charades Games started. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in parent reported social responsiveness from week 0 to week 12 | Baseline (Week 0), Week 12 | The Social Responsiveness Scale-2 is a 65-item measure where parents rate their child selecting responses on a Likert Scale. This measure will be used to measure and identify social impairment associated with Autism Spectrum Disorder (ASD) and to quantify its severity Social Responsiveness Scale (SRS) raw scores measure social abilities with lower scores indicating better social skills. (Raw Score Range: 0 - 195 and T-Score Range: 37- above 90). |
| Change in mobile autism risk assessment score from week 0 to week 12 | Baseline (Week 0), Week 12 | A level 2 screening tool that has been validated in several studies and that uses a brief parent questionnaire with a 2 minute home video to generate a classification score that indicates severity of the autism phenotype (ranging from no autistic symptoms to severe autism) as well as confidence in the classification. |
Countries
United States
Outcome results
None listed