White Matter Disease
Conditions
Brief summary
Patients meeting the inclusion and non-inclusion criteria will be offered to participate in the study. If they agree, they will perform an MRI without injection to obtain the QSM then perform the MRI with injection that was prescribed to them as part of the care, then they will perform a second time the MRI without injection to obtain the QSM. They will also answer a short questionnaire documenting their previous exposure to gadolinium.
Detailed description
Patients meeting the inclusion and non-inclusion criteria will be offered to participate in the study. If they agree, they will perform an MRI without injection to obtain the QSM then perform the MRI with injection that was prescribed to them as part of the care, then they will perform a second time the MRI without injection to obtain the QSM. They will also answer a short questionnaire documenting their previous exposure to gadolinium.
Interventions
DEVICEMRI
SWI QSM 1.0iso 8 echos sequence performed before and after the injected MRI prescribed as part of the treatment. \* Sense 2 \* 2: 9min33s
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients over 18 years old * with an inflammatory CNS pathology * to benefit as part of care from an MRI with injection of gadolinium * consent to participate in the study * beneficiary of a social protection scheme
Exclusion criteria
* pregnant or breastfeeding woman * patient benefiting from a legal protection measure * Patient having performed more than 3 MRI exams with gadolinium injection during his life Secondary
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| mean of the delta observed between the QSM of the white matter before and after injection of gadolinium | 1 DAY | mean of the delta observed between the QSM of the white matter before and after injection of gadolinium |
Countries
France
Outcome results
None listed