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Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure

Correlation Between Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04906161
Enrollment
30
Registered
2021-05-28
Start date
2021-01-20
Completion date
2022-06-30
Last updated
2021-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implant Failure Nos, Vitamin D Deficiency

Brief summary

In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D.

Detailed description

Osseointegration is a complex phenomenon and depends on many factors; some are related to the implant (material, macroscopic design, and implant surface), others to the surgical-prosthetic protocol (surgical technique, loading conditions, and time), and others to the patient (quantity/quality of bone at the receiving site and the host response) All these observations would suggest the existence of specific patient-related risk factors such as vitamin D deficiency in the blood, could play an important role in the occurrence of early dental implant failures (EDIFs), but unfortunately are neglected by the dental literature. In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D. Therefore we are including patients with early implant failure during the year 2020 using the same implant (material, macroscopic design, and implant surface), surgical-prosthetic protocol (surgical technique, loading conditions, and time) The study will be performed into 15 male and 15 female participants that had dental implant placement in the last 3 months. An informed consent will be signed with the patient with full detail on the study. The situation of the implant will be categorized into either successful or failed dental implant. Medical history and lifestyle information will be obtained by questionnaire. Levels of serum vitamin D will be collected from participants Statistical analysis will correlate between vitamin D and early implant failure.

Interventions

DIAGNOSTIC_TESTVitamin D and calcium levels

Mini VIDAS® compact multiparametric immunoanalyzer for vitamin D analysis (BIOMERIEUX- France)

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Missing single tooth * Systemically free * Average body mass index

Exclusion criteria

* Systemic conditions * Bad oral hygiene

Design outcomes

Primary

MeasureTime frameDescription
Implant success with normal serum vitamin D level6 monthsImplant stability with no further radiographic bone loss following bone remodeling with successful prosthetic part
Early implant failure with deficient serum vitamin D level6 monthsMobile extruded implant with radiographic bone loss and peri-implant pathosis

Countries

Egypt

Contacts

Primary ContactDoaa Adel-Khattab, PhD
dr.doaa.adel-khattab@dent.sasu.edu.eg+201006814258

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026