Safety Issues
Conditions
Brief summary
Non critical hospitalized patients were bathed daily with 4 substances: bleach at .005%, bleach at .0125%, clorhexidine 2% and soap and water. 76 patients were enrolled and divided 19 subjects per group. Each patient was cultured with swab technique in palm, antecubital fold and armpit at day 0, day 3 and day 7 of enrollment. Bacterial cultures were incubated and compared if decolonization occurred. Adverse events were evaluated in all patients. Only 1 patient had and adverse event and was dry skin. Before patient was enrolled, he had dry skin because of his baseline disease. Moisturizing lotion was applied and patient continue in the study.
Interventions
None listed
Sponsors
Hospital Universitario Dr. Jose E. Gonzalez
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Non critical hospitalized patients in internal medicine * 18 years old and older
Exclusion criteria
* Burn patients * Pregnant women * Chloride hypersensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of Bleach baths as determined by the incidence of adverse or serious adverse events | November 26, 2019 - October 25, 2020 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Identification of bacterial colonization from pathogens belonging to the ESKAPE group | November 26, 2019 - October 25, 2020 | Identification of colonization by Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species |
| Percentage of patients remaining colonized 3, 5 and 7 days after daily baths | November 26, 2019 - October 25, 2020 | — |
Countries
Mexico
Outcome results
None listed