Multi-center Research Project for Glioma Molecular Pathology Intraoperative Rapid Detection

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04904419

Enrollment

137

Registered

2021-05-27

Start date

2021-08-01

Completion date

2022-01-31

Last updated

2023-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioma, Malignant

Brief summary

We explores the accuracy and sensitivity of rapid intraoperative detection of IDH, TERT, BRAF indicators through a prospective clinical multi-center study. This part includes a total of 300 fresh tissue samples, paired blood samples, relevant clinical information and follow-up information from 300 patients with different grades of adult glioma. By comparing with the postoperative sequencing results, the specificity and sensitivity of intraoperative IDH and TERT rapid detection results are clear.

Interventions

DIAGNOSTIC_TESTIntraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e

Intraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* 1\. Glioma patients with Informed Consent Form 2. Glioma patients with intact clinical information

Exclusion criteria

* 1\. Glioma patients without Informed Consent Form 2. Glioma patients without intact clinical information

Design outcomes

Primary

Measure	Time frame
Intraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e	Intraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026