Anesthesia
Conditions
Keywords
laser, anesthesia, bispectral index, postoperative delirium
Brief summary
Investigators analyze the anesthesia of the endolaryngeal laser surgery in patients with smoking with or without monitoring of depth of anesthesia (bispectral index)
Detailed description
All participants are informed about the investigation and are signed the Informed Consent before anesthesia. The study takes place at the Department of Otorhinolaryngology, University of Pecs, Hungary. Between June 2021 and May 2022 ASA I or II patients aged 18-65 years, scheduled for elective endolaryngeal laser surgery with TCI (target-controlled infusion, propofol). Exclusion criteria are epilepsy, psychiatric illness, cerebrovascular or congenital neuromuscular disease. Participants are randomized to two anesthetic groups, anesthesia with or without bispectral index monitoring.
Interventions
intraoperative single-channel electroencephalography monitoring of the depth of anesthesia
Sponsors
University of Pecs
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Masking description
anesthesia with target-controlled infusion (propofol) with or without the depth of anesthesia (bispectral index) monitoring and evaluation of vital parameters, side effects, and postoperative delirium
Intervention model description
the side effects of endolaryngeal laser surgery's anesthesia with or without bispectral index monitoring in patients with smoking
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* endolaryngeal laser surgery with target-controlled anesthesia
Exclusion criteria
* epilepsy, psychiatric illness, cerebrovascular or congenital neuromuscular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| circulation | through study completion, an average of 1 year | blood pressure (mmHg) |
| cardiac function | through study completion, an average of 1 year | pulse rate (beats/minute) |
| oxygenization | through study completion, an average of 1 year | oxygen saturation (%) |
| ventilation | through study completion, an average of 1 year | end-tidal carbon-dioxide (mmHg) |
| depth of anesthesia | through study completion, an average of 1 year | bispectral index level (number between 1-100), the target intraoperative level 40-60, lower and higher are worse |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| cognitive functions | through study completion, an average of 1 year | cognitive functions test (Montreal Cognitive Assessment) score (number between 0-30, minimum=0, maximum=30), higher number is better |
Countries
Hungary
Outcome results
None listed