Assessment of the Impact of Acquisition Time, Respiratory Gating and New Qclear Reconstruction Modalities on the Quantification of Dosimetry in Selective Internal Radiotherapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04903340

Acronym

PYR

Enrollment

Registered

2021-05-26

Start date

2021-04-12

Completion date

2021-12-10

Last updated

2022-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carcinoma, Hepatocellular

Brief summary

Post-processing of Positron Emission Tomography (PET) acquired images, performed following radioembolization treatment with microspheres at 90Y in hepatocellular carcinoma patients, is subject to changes commercialized by General Electric : respiratory motion correction, specific reconstruction algorithms. We propose to test the possible combinations of these reconstruction parameters to determine which ones to apply for an optimal quality exam with the shortest scan time possible

Interventions

PROCEDUREPET/CT Exam

PET/CT image processing application of reconstruction parameters: scan time, respiratory gating, Q-clear

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patient with hepatocellular carcinoma * with radioembolization treatment decided * over the age of 18

Exclusion criteria

* radiembolization not possible * acquisition of PET/CT imaging at 90Y not possible

Design outcomes

Primary

Measure	Time frame
Average dose value (Gy) of tumor liver and healthy liver obtained according to reconstruction configuration.	Day 0 (PET/CT Exam)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026