Carotid Artery Diseases, Coronary Artery Disease, Stroke
Conditions
Brief summary
A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months. The rate of postoperative stroke and complications was compared between CEA performed under Local anaesthetic (LA) to those performed under General anaesthetic (GA).
Detailed description
The primary outcome was the rate of postoperative stroke in patients that had staged CEA prior to CABG. This was defined as CEA within a period of 4 weeks prior to CABG. We retrospectively looked at those patients that fulfilled the inclusion criteria and had CEA performed either under LA (Group A) or under GA (Group B). We measured the 30 days' postoperative stroke rate as the main outcome. We also looked at the rate of intraoperative stroke. Additionally, we assessed the rate for developing nerve injuries and/or hematoma postoperatively. Finally, we examined the risk for developing postoperative stroke in patients with bilateral significant carotid artery disease that underwent surgery in one side.
Interventions
PROCEDURECarotid endarterectomy
Carotid endarterectomy prior to CABG operations either under Local Anaesthetic or under General Anaesthetic.
Sponsors
University Hospital Birmingham
Thomas Aherne
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
\- All patients that had carotid endarterectomy performed in staged fashion within 6 months before a CABG operation.
Exclusion criteria
* Patients diagnosed with symptomatic carotid disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stroke | 30 days | a transient ischaemic attack (TIA), or a disabling stroke within 30 days of the carotid endarterectomy procedure. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Major bleeding | 30 days | Major haematoma was defined as a significant bleeding that required the patient to go back to theatre for a secondary procedure. |
| Minor bleeding | 30 days | A minor hematoma was defined as bleeding that resulted in bruising and neck swelling without causing significant concerns to require a secondary procedur |
| Nerve injuries | 30 days | Either neuropraxia that resolved with time or permanent injuries that resulted in disability. |
Outcome results
None listed