Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy

Efficacy and Safety of Granisteron Versus Metoclopramide as Prophylaxis Antiemetic in Laparoscopic Cholecystectomy

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04899817

Enrollment

Registered

2021-05-25

Start date

2021-05-31

Completion date

2022-04-30

Last updated

2021-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and Vomiting, Postoperative

Keywords

Laparoscopic cholecystectomy

Brief summary

Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy

Detailed description

Post operative nausea and vomitting is Avery common complication of laparoscopic surgery in that study we will compare between granisteron and metoclopramide as aprophlaxis against post operative nausea and vomitting

Interventions

DRUGGranisetron

The drug is given after induction of general anesthesia

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* both sexes Age between 18 and 60 years ASA1 2 3 Lap cholecystectomy under general anesthesia

Exclusion criteria

* patients refusal Pregnancy and breastfeeding Hepatic or renal disease ASA4 5 Allergy to the drug

Design outcomes

Primary

Measure	Time frame	Description
Postoperative nausea and vomitting	Every 2 hours for 12 hours	Number of attacks of nausea and vomitting

Countries

Egypt

Contacts

Primary ContactLayali Dardeer

as0296856@gmail.com01096928662

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026