Taste Disturbance After Middle Ear Surgery: Frequency, Duration, Influence of Chorda Tympani Injury and Quality of Life

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04899011

Enrollment

214

Registered

2021-05-24

Start date

2021-05-30

Completion date

2023-05-23

Last updated

2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ear Middle Problems

Brief summary

Chorda tympani nerve (CTN), is a branch of nerve VII, and has two componants: taste sensation from the anterior two thirds of the tongue and salivary secretion from submandibular and sublingual salivary glands. CTN go throw middle ear between malleus and incus. Due to it anatomic localization, CTN is frequently damage during otologic surgery. Taste disturbance after middle ear surgery has been describe in literature but results of the various studies are very heterogenous. Moreover, there is no consensus to preserved or sacrificed a traumatize CTN. We will use questionnaire to evaluate frequency, duration and characteristics of taste disturbance after ear surgery and the impact on the quality of life for those with symptoms. We will evaluate the Influence of type of CTN injury on taste disturbance.

Interventions

OTHERQuestionnaire

Questionnaire about taste and salivary disturbance before surgery, 10 days, 4 months and 1 year after surgery. Questionnaires include characteristics of taste disturbance, and specific impact on quality of life.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patient undergoing middle ear surgery * Acceptation to participate * under 18 years old, parental authorization.

Exclusion criteria

* Taste disturbance before surgery * Patients with guardianship or tutelage measure

Design outcomes

Primary

Measure	Time frame	Description
Frequency, duration and characteristics of taste and salivary disturbance after middle ear surgery and impact on quality of life.	1 year	Taste and salivary disturbance will be measure with questionnaire before and during 1 year after middle ear surgery

Secondary

Measure	Time frame	Description
Influence of CTN injury type: stretch versus sectionned, influence of otologic desease	1 day	Measure with surgeon questionnaire
Influence of use between endoscope or microscope surgery	1 day	Measure with surgeon questionnaire

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026