Active Older Adult Program on Health and Well-being

The Effects of an Active Older Adult Program at the Dan Abraham Healthy Living Center on Health and Well-being

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04897373

Enrollment

Registered

2021-05-21

Start date

2018-08-07

Completion date

2020-04-02

Last updated

2021-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Older Adult

Brief summary

The purpose of this study is to determine whether a structured 12-week program designed for older adults will improve physical function and, in parallel, circulating biomarkers of aging

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

55 Years to No maximum

Healthy volunteers

Inclusion criteria

* Men and women age 55 years or older. * Membership at the DAHLC. * New to AOA (Active Older Adult) Program and commitment to full participation in the twelve-week program. * Must be able to get down and off the floor with little assistance.

Exclusion criteria

* Inability to provide informed consent. * Previous participation in the AOA Program at the DAHLC.

Design outcomes

Primary

Measure	Time frame	Description
Change in repeated chair rise time	Baseline to end of study, approximately 14 weeks	Chair stand test where participants will perform a chair rise movement for five repetitions. The series of 5 repetitions will be timed and measured in seconds.
Change in plasma protein levels reflective of biological age	Baseline, week 12	Blood samples will be obtained at baseline and at 12 weeks. The concentration of target proteins (pg/mL) in the plasma will be measured and compared between baseline and week 12.
Change in expression of senescence-related genes in blood cells	Baseline, week 12	Blood samples will be obtained at baseline and at 12 weeks. The expression of senescence-related genes (arbitrary units) will be measured in immune cells isolated from whole blood and compared between baseline and week 12.

Secondary

Measure	Time frame	Description
Change in Self-reported Physical Function	Baseline, week 12	Measured using the Physical Component Scale (PCS) from the 12-Item short form general health survey (SF-12).
Change in self-assessment of well-being	Baseline, week 12	Measured using a linear analogue self-assessment scale of well-being from 0 (as bad as it can be) to 10 (as good as it can be) of mental, physical, emotional, and spiritual well-being, level of social activity, and overall quality of life during the past week
Change in Performance-based Physical Function	Baseline, week 12	Measured using the timed up-and-go test (seconds to complete).
Change in Mental Function	Baseline, week 12	Measured using the Mental Component Scale (MCS) from the 12-Item short form general health survey (SF-12)

Countries

United States

Outcome results