Direct Use of Non-centrifuged Autologous Fat Graft

Direct Use of Autologous Fat Graft on The Treatment of Lower Extremity Wounds

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04896437

Enrollment

Registered

2021-05-21

Start date

2016-03-02

Completion date

2020-03-18

Last updated

2021-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Healing Delayed

Keywords

diabetic food, lower extremity, fat graft, nonentrifuged

Brief summary

There are a limited number of reports related to the direct use of non-centrifuged adipose tissue graft in the literature. This preliminary study aims to present our experience on the efficacy of autologous fat graft use without centrifuging in the treatment of lower extremity wounds.

Detailed description

16 wounds treated with non-centrifuged autologous fat grafts were included in the study. The data were retrospectively analyzed. VAC (vacuum-assisted therapy) or silver-impregnated dressing was used to achieve a healthy wound bed before fat grafting. Autologous fat grafts were harvested from abdominal or gluteal regions of the patients and injected into the wound bed and wound environment. Clinical observation and photograph records were used to follow the wounds.

Interventions

PROCEDUREnon-centrifuge fat graft application to the wounds

Autologous fat grafts were harvested from abdominal or gluteal regions of the patients and injected into the wound bed and wound environment. Clinical observation and photograph records were used to follow the wounds.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 65 Years

Healthy volunteers

Inclusion criteria

1. diabetic, 2. venous 3. traumatic wounds

Exclusion criteria

1. Malignancy, 2. A life expectation \<1 year, 3. Chemical or radiation exposure. 4. Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Wounds examination	6 months	Collection of the data from clinical observation and photograph records were made to follow the wounds. the observations were made during changing the wound dressing and generally every three days.

Secondary

Measure	Time frame	Description
Wounds classification according to data from files and photographs	3 months	In this season the data will be classified according to the wounds parameters and photograph
Final evaluation and data achieving from files and exam carts	3 months	all data will be examined and evaluated whether there is any difference between probable groups

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026