Injection Rate and Erector Spinae Plane Block

Effect of Injection Rate on the Block Sensory Level in the Erector Spine Plane Block

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04895072

Enrollment

Registered

2021-05-20

Start date

2021-05-17

Completion date

2021-11-30

Last updated

2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain, Breast Surgery

Keywords

Erector spinae plane (ESP) block, Postoperative Pain, Breast Surgery

Brief summary

To evaluate the effect of injection rate on the block sensory level in the ESP block.

Detailed description

Many women experience severe acute postoperative pain after breast cancer surgery. Regional techniques are frequently used as a part of multimodal analgesia in breast surgery. Ultrasound-guided erector spinae plane (ESP) block is a preferred method to reduce the postoperative opioid requirement for postoperative pain management. In this study, we aimed to evaluate the effect of injection rate on the block sensory level in the ESP block.

Interventions

PROCEDUREStandard group

Ultrasound-guided ESP block with 20 mL %0.375 bupivacaine will be administered at a standard injection rate.

PROCEDURELong group

Ultrasound-guided ESP block with 20 mL %0.375 bupivacaine will be administered at a long injection rate.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* aged between eighteen and sixty-five * ASA I-III * undergo elective breast cancer surgery

Exclusion criteria

* under 18 years of age or over 65 years of age * ASA IV and above * declined to give written informed consent * contraindications of peripheral blocks or local anesthetic infiltration * history of allergy against local anesthetics * chronic pain history * history of hepatic, neuromuscular, cardiac and/or renal failure * infection at the injection site

Design outcomes

Primary

Measure	Time frame	Description
Block sensory level	12 hours	Number (average) of dermatomes with sensory block with pinprick and cold methods after the ESP block

Secondary

Measure	Time frame	Description
Postoperative tramadol consumption	24 hours	Postoperative tramadol consumption will be recorded at 24 hours
Assesment of postoperative analgesia	24 hours	Post operative pain scores will be assessed using a numerical rating scala (NRS) (from 0=no pain, to10= worst pain imaginable).

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026