Prehabilitation and Rehabilitation for Patients With Oesophageal Cancer

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04894149

Acronym

PRESO

Enrollment

Registered

2021-05-20

Start date

2021-04-22

Completion date

2023-05-31

Last updated

2021-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer

Brief summary

Patients with oesophageal cancer selected for oncological and surgical treatment with curative intent are offered supervised physiotherapy and home-based training before and after surgery.

Detailed description

Patients with loco-regional oesophageal cancer who will receive neoadjuvant chemotherapy or chemoradiotherapy followed by surgery and sometimes adjuvant chemotherapy are eligible to be enrolled in the trial. Study treatment is supervised group training twice weekly and home-based training three times weekly during neoadjuvant treatment and after surgery.

Interventions

OTHERPhysiotherapy

Supervised physiotherapy one hour twice weekly and 20 minutes three times weekly during 14- 17 weeks before surgery during neoadjuvant chemotherapy or chemoradiotherapy and during eight weeks after surgery (sometimes during adjuvant chemotherapy)

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Histopathologically confirmed squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma in the oesophagus or cardia (Siewert I or II), cT1 N+ or cT2-4a any N, M0, according to the 8th version of the AJCC TNM classification. * Assessed at a multidisciplinary conference to be suitable for curatively intended oncological and surgical treatment. * Age \> 18 years. * Performance status ECOG 0-2. * Patient has provided written informed consent.

Exclusion criteria

* Previous radiotherapy in the thorax (except for tangential field radiotherapy for breast cancer). * Inability to understand written and spoken instructions and to comply with protocol requirements.

Design outcomes

Primary

Measure	Time frame	Description
Adherence to exercise sessions.	Up to 40 weeks	Percentage of sessions completed out of number of sessions planned
Un-planned interruptions in the prehabilitation/rehabilitation programme	Up to 40 weeks	Percentage of patients having an unplanned interruption of ten days or more of the supervised prehabilitation/rehabilitation programme

Countries

Sweden

Contacts

Primary ContactGabriella A von Döbeln, MD, PhD

+46 8 517 700 00

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026