Low Back Pain in Obese Patients After Important Weight Loss
Conditions
Keywords
Bariatric, Spine, Obese, Low back pain, Sagittal alignment, Lipomatosis
Brief summary
The purpose of this study is to determine how an important weight loss after bariatric surgery affects obese patients ' spine, and the effects it has on low back pain, sagittal alignment and lipomatosis .
Detailed description
Obesity and back pain are massive public health problems, and the relationship between the two has not been described and studied. However, the investigators have also observed that many ex-obese patients still suffer from back and leg pain after an important weight loss. The aim of this study is to measure the effect of weight loss on back pain, and to find out what parameters can explain such modifications (increasing or decreasing back pain). The investigators will study clinical parameters, as well as radiological (to measure the effect of weight loss on spine sagittal alignment) and MRI (to measure lipomatosis, which is a fat epidural accumulation, responsible for nerve compression and therefore back and leg pain).
Interventions
DIAGNOSTIC_TESTFull Spine Radiography
Full Spine Radiography
DIAGNOSTIC_TESTLumbar spine MRI
Lumbar spine MRI
Sponsors
Sauver La Vie
URC-CIC Paris Descartes Necker Cochin
Assistance Publique - Hôpitaux de Paris
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> 18 years old * BMI \> 40 or BMI \> 35 with comorbidities due to obesity ( criteria for bariatric surgery) * Follow up in Pompidou's Hospital Nutrition service * Bariatric surgery intervention ( Sleeve gastrectomy or By pass) * Follow up possible for one year or more * Being covered by French social insurance * Consent to participate in the study
Exclusion criteria
* History of spine surgery * Bariatric surgery postoperative complication * Non mastering of french language * MRI contraindication * Patient under legal protection ( e.g. guardianship)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oswestry disability Index (ODI) | 1 year postoperative | Clinical score to evaluate low back pain vs Preoperative evaluation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sagittal alignment | 6 months postoperative | Radiologic measurement of spine parameters vs Preoperative evaluation |
| Disc degeneration | 6 months postoperative | MRI evaluation vs Preoperative evaluation |
| Lipomatosis | 6 months postoperative | MRI evaluation of lumbar epidural fat accumulation vs Preoperative evaluation |
| Oswestry disability Index (ODI) | 6 months postoperative | Clinical score to evaluate low back pain vs Preoperative evaluation |
| Neck disability Index (NDI) | 6 months postoperative | clinical score to evaluate neck pain vs Preoperative evaluation |
| Short Form 12 (SF12) | 6 months postoperative | Score to evaluate quality of life vs Preoperative evaluation |
| Hospital anxiety and depression (HAD) scale | 6 months postoperative | Score to evaluate depression vs Preoperative evaluation |
| Visual Analog Scale (VAS) | 6 months postoperative | Clinical score to evaluate low back pain vs Preoperative evaluation |
Countries
France
Contacts
Primary ContactEmmanuelle FERRERO, MD, PHD
Backup ContactMarie BENHAMMANI-GODARD
Outcome results
None listed