Relationship of Skeletal Muscle Thickness, Strength, and Diaphragm Function in Adults With CF

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04892485

Enrollment

Registered

2021-05-19

Start date

2017-09-01

Completion date

2018-04-30

Last updated

2021-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis

Keywords

CF, nutritional status, peripheral muscle thickness, peripheral muscle strength, diaphragm thickening fraction

Brief summary

31 CF patients and 23 healthy sex and age-matched volunteers were enrolled. All subjects underwent pulmonary function tests, 6-minute walking tests. Body Mass Index and Fat Free Mass Index were measured via a body composition analyser. Diaphragm ultrasonography (to measure thickening fraction), quadriceps femoris muscle ultrasonography were performed. A dynamometer was used to measure each subjects handgrip strength.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* CF diagnosed * Age 18 and above

Exclusion criteria

* Having a pulmonary flare up within the previous month * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Muscle Thickness, Strength and Diaphragm Thickening Fraction of CF Patients	2 months	Measured via USG and handheld dynamometer

Countries

Turkey (Türkiye)

Outcome results