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Sphenopalatine Ganglion Block for Postdural Puncture Headache

Effectiveness of Sphenopalatine Ganglion Block on Postdural Puncture Headache Treatment: A Retrospective Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04892290
Enrollment
110
Registered
2021-05-19
Start date
2019-12-01
Completion date
2020-05-19
Last updated
2021-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postdural Puncture Headache

Keywords

Sphenopalatine Ganglion Block, Postdural Puncture Headache

Brief summary

Background: Postdural puncture headache (PDPH), which is one of the complications of spinal anesthesia, is a condition that negatively affects the quality of life of patients, causes late mobilization and prolonged hospital stay. Sphenopalatine ganglion block (SGB) has created a minimally invasive, easy, and safe treatment alternative. Objective: Evaluating the effectiveness of topical SGB on PDPH treatment. Design: Retrospective observational study Setting: Single center tertiary level of care hospital study. The files of PDPH patients between Jan 2018 and Jan 2020 were scanned. Patients: PDPH patients aged 18-65 are included and any patients with primary/secondary headache history are excluded. Main outcome measures: Patients were divided into 2 groups. The group that given only conservative treatment was named as Group C, and the group of patients who had additionally been applied SGB was named as Group SGB. Headache severity was measured with Visual Analogue Scale (VAS) at the 1st,3rd, 12th and 24th hours of the treatment, in supine and upright position.

Interventions

OTHERConservative Treatment for Postdural Puncture Headache

The patients in Group C were given continuous bed rest in the supine position, 3000 mL daily hydration, 6 mg kg-1 aminophylline , 2 g day-1 paracetamol and 65 mg day-1 caffeine as conservative treatment. Topical SGB was applied to patients in Group SGB in addition to conservative treatment.

Sponsors

Sakarya University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* 18-65 years-old * not having any headache diagnosis (G44 and subgroup according to the International Classification of Diseases-10 classification), * developed PDPH according to the International Headaches Classification after the neuraxial procedure

Exclusion criteria

* history of primary headaches such as migraine, cluster type, tension type * secondary headache such as preeclampsia / eclampsia, cerebral venous thrombosis, stroke, ruptured aneurysm, hypertensive encephalopathy, pituitary apoplexy, meningitis and subarachnoid hemorrhage * any local or systemic infection

Design outcomes

Primary

MeasureTime frameDescription
Headache in Supine Position1st, 3rd, 12th and 24th hours of follow-upHeadache severity changes with Visual Analogue Scale (VAS, 0-10, 0: no pain, 10:worst pain)

Secondary

MeasureTime frameDescription
Headache in Prone Position1st, 3rd, 12th and 24th hours of follow-upHeadache severity changes with Visual Analogue Scale (VAS, 0-10, 0: no pain, 10:worst pain)
Successfully treated patients ratio24th hour of follow-upAt the 24th hour of their follow-up, all patients with a VAS\>3 (Visual Analogue Scale) headache in an upright position are considered as unsuccessful treatment and are directed to the epidural blood patch procedure. Both groups will be compared with successfully treated patients ratios.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026