Cancer Gi, Cancer of Endometrium, Systemic Immune Activation
Conditions
Brief summary
The effects of different anesthesia methods on the immune system are variable. In this study, we investigated the effect of inhalation anesthesia and total intravenous anesthesia on the SII value in major abdominal cancer surgeries.
Detailed description
The study was planned prospectively, observationally, on a total of 90 patients who underwent major abdominal cancer surgery. 84 patients were evaluated. The patients were seperated in two groups as inhalation anesthesia and total intravenous anesthesia (TIVA). The demographic data of the patients, type of cancer, type of surgery performed, ASA classification, preoperative chemotherapy intake, preoperative hemogram, postoperative 2nd and 24th hour hemogram, intraoperative and postoperative blood transfusion, and duration of surgery were recorded. Platelet, neutrophil, lymphocyte and SII values were saved.
Interventions
OTHERSystemic inflammatory immmune index
Systemic Inflammatory Immune index calculated from platelet, neutrophil and lymphocyte count
Sponsors
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* major abdominal cancer surgeries
Exclusion criteria
* blood transfusion in last 72 hours * patients with infection * hematologic malignancy * patient controlled analgesia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| investigate the effect of anesthesia management on the change of preoperative systemic inflammatory immune index(SII) and postoperative 2.hour and 24.hour SII value | preoperative SII noted, postoperative 2.hour noted and postoperative 24.hour noted | systemic inflammatory immune index calculated by (platelet x neutrophil)/lymphocyte |
Countries
Turkey (Türkiye)
Outcome results
None listed