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Symptom Clusters in Hong Kong Chinese Children With Blood Cancer

Symptom Clusters in Hong Kong Chinese Children With Blood Cancer:: A Longitudinal Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04888195
Enrollment
120
Registered
2021-05-17
Start date
2021-09-01
Completion date
2024-09-01
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child

Keywords

blood cancer, chemotherapy

Brief summary

Pediatric blood cancer is the most common childhood malignancy. Despite its survival has been substantially improved, children still have to pay a high price for numerous distressing symptoms resulted from chemotherapy. Previous studies related to symptom experiences mainly focus on individual symptoms, rather than on multiple symptoms. Understanding these distressing symptoms may help healthcare professionals to develop appropriate and effective interventions with the aims of alleviating symptom severity and thus promoting the child's psychosocial well-being and quality of life.

Detailed description

A longitudinal study design will be conducted. A sample of 120 patients age 5-17years, diagnosed with blood cancer but not yet receive any chemotherapy and able to communicate with Cantonese and read Chinese will be recruited in the pediatric oncology ward of Hong Kong Children's Hospital.

Interventions

OTHERQuestionnaire

Participants will complete a set of validated questionnaires (TRSC-C and demographic sheet) before chemotherapy. They also have to complete the same questionnaires (TRSC-C) again within 1 week after the 1st, 2nd, 3rd, 4th , 5th and 6th courses of chemotherapy via telephone interview by our research assistants.

Sponsors

The Hong Kong Polytechnic University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* aged 5 - 17 years old * diagnosed with blood cancer but not yet receive any chemotherapy * able to communicate with Cantonese and read Chinese

Exclusion criteria

* who are scheduled to have concurrent cancer treatment * with recurrent malignancy * medical condition, or cognitive and learning problems in their medical records

Design outcomes

Primary

MeasureTime frameDescription
The therapy-related symptom checklist for children (TRSC-C)Before chemotherapyFor measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 1-weekAt 1-week follow-upFor measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 1-monthAt 1-month follow-upFor measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 3-monthAt 3-month follow-upFor measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
The therapy-related symptom checklist for children (TRSC-C) at 6-monthAt 6-month follow-upFor measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
Demographic sheetAt baselinecollect the background information of our subjects, including their age, gender, educational attainment, parents' marital status and religious belief

Countries

Hong Kong

Contacts

Primary ContactKa Yan Ho, PhD
kyeva.ho@polyu.edu.hk27666417
Backup ContactKa Wai Lam, PhD
kwkatlam@polyu.edu.hk27666420

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026