Child
Conditions
Keywords
blood cancer, chemotherapy
Brief summary
Pediatric blood cancer is the most common childhood malignancy. Despite its survival has been substantially improved, children still have to pay a high price for numerous distressing symptoms resulted from chemotherapy. Previous studies related to symptom experiences mainly focus on individual symptoms, rather than on multiple symptoms. Understanding these distressing symptoms may help healthcare professionals to develop appropriate and effective interventions with the aims of alleviating symptom severity and thus promoting the child's psychosocial well-being and quality of life.
Detailed description
A longitudinal study design will be conducted. A sample of 120 patients age 5-17years, diagnosed with blood cancer but not yet receive any chemotherapy and able to communicate with Cantonese and read Chinese will be recruited in the pediatric oncology ward of Hong Kong Children's Hospital.
Interventions
Participants will complete a set of validated questionnaires (TRSC-C and demographic sheet) before chemotherapy. They also have to complete the same questionnaires (TRSC-C) again within 1 week after the 1st, 2nd, 3rd, 4th , 5th and 6th courses of chemotherapy via telephone interview by our research assistants.
Sponsors
Study design
Eligibility
Inclusion criteria
* aged 5 - 17 years old * diagnosed with blood cancer but not yet receive any chemotherapy * able to communicate with Cantonese and read Chinese
Exclusion criteria
* who are scheduled to have concurrent cancer treatment * with recurrent malignancy * medical condition, or cognitive and learning problems in their medical records
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The therapy-related symptom checklist for children (TRSC-C) | Before chemotherapy | For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment. |
| The therapy-related symptom checklist for children (TRSC-C) at 1-week | At 1-week follow-up | For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment. |
| The therapy-related symptom checklist for children (TRSC-C) at 1-month | At 1-month follow-up | For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment. |
| The therapy-related symptom checklist for children (TRSC-C) at 3-month | At 3-month follow-up | For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment. |
| The therapy-related symptom checklist for children (TRSC-C) at 6-month | At 6-month follow-up | For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment. |
| Demographic sheet | At baseline | collect the background information of our subjects, including their age, gender, educational attainment, parents' marital status and religious belief |
Countries
Hong Kong