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Studies of the Angle Kappa and the Angle Alpha

Studies of the Characteristics of the Angle Kappa and the Angle Alpha in the Healthy Individual. Studies of the Angle Kappa and the Angle Alpha

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04886219
Acronym
EKAPS
Enrollment
70
Registered
2021-05-14
Start date
2021-05-19
Completion date
2021-10-04
Last updated
2025-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

No Eye Disorder

Keywords

Angle Kappa, Angle Alpha, Pupillary axis, Visual axis, Optical axis

Brief summary

Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive...) or in clinical practice. The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination. The aim of the study is to analyze the correlation between the angle alpha and the angle kappa in a healthy individual without ophthalmologic disorder.

Detailed description

The angle kappa corresponds to the angle formed between the visual axis (line between the point of fixation and the fovea: area of the retina allowing precise vision) and the pupillary axis (line passing through the center of the pupil and perpendicular to the cornea). The angle alpha corresponds to the angle formed between the visual axis and the optical axis (line passing through the nodal point of the eye and corneal center). In theory, the angle kappa and angle alpha are equal; but physiological corectopy in the nasal position induces a variation between these two angles; the angle kappa being generally less than the angle alpha without a correlation being established. Also, pupillary constriction causes a variation in the position of the center of the pupil. The angle kappa therefore exhibits a variation depending on the expansion. Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive ...) or in clinical practice. The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination. The aim of the study is to analyze the correlation between the angle alpha and the angle kappa in a healthy individual without an eye disorder.

Interventions

* Multimodal fundus imaging (color fundus photography, optical coherence tomography (OCT)) * orthoptic assessment (Visual acuity, Refraction, Cover test, Stereopsis evaluation * ocular biometry * corneal topography * monocular photographs in photopic and scotopic condition

Sponsors

URC-CIC Paris Descartes Necker Cochin
CollaboratorOTHER
Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- Informed major subject not opposing to their participation in the study

Exclusion criteria

\- Subject with strabismus or organic ophthalmologic pathology

Design outcomes

Primary

MeasureTime frameDescription
Value of the angle KappaDay 0Semi-automatic digital method of measurement by eye photography
Value of the angle AlphaDay 0Semi-automatic digital method of measurement by eye photography

Secondary

MeasureTime frameDescription
Variation of the Kappa angle depending on the pupillary diameterDay 0Variation in the same individual. Value of the Kappa angle using the semi-automatic method of measurement by ocular photography in photopic and scotopic conditions & measurement of the pupillary diameter using the photographs obtained
Correlation between the value of the angle Alpha and the Optic disc / fovea distanceDay 0Angle Alpha value using the semi-automatic method of measurement by eye photography and the distance between the optic disc and the fovea
Correlation between the angle Kappa and the axial lengthDay 0Value of the angle Kappa and Alpha using the semi-automatic method of measurement by eye photography and Value of the axial length measured by biometry IolMaster 500 (Carl Zeiss)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026