Post-induction Hypotension
Conditions
Brief summary
Hypotension after induction of general anesthesia and before surgical stimulation is a prevalent anesthesia-related side effect. The post-induction hypotension disrupts organ perfusion and may cause organ damage particularly acute kidney injury, cerebrovascular stroke, and myocardial ischemia. Post-induction hypotension occurs with greater frequency and severity in the elderly. This is because of aged-related diminished cardiac reserve and impaired autonomic homeostasis. Pleth variability index (PVI) is a software program that measures the dynamic changes of the PI that occurs during a complete respiratory cycle. Our primary outcome is to determine the predictive ability and the optimal cut-off value of pre-anesthesia PVI for predicting elderly patients who are at risk of developing post-induction hypotension
Interventions
DEVICEPleth variability index for prediction of post-induction hypotension
The use of the baseline Pleth variability index values for prediction of occurrence of post-induction hypotension
Sponsors
Cairo University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* patients with ASA physical status I or II * patients will receive general anesthesia
Exclusion criteria
* Patients with a history of cardiorespiratory disorders * patients with uncontrolled hypertension or cardiac dysrhythmias * Patients with renal or hepatic diseases. * Patients with long-standing diabetes and peripheral vascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The accuracy (Area under receiver operating characteristic curves) of pre-induction PVI for prediction of post-induction hypotension | before induction of general anesthesia |
Countries
Egypt
Outcome results
None listed