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Factors Affecting the Time to Start Postoperative Chemotherapy in Colorectal Cancer

Factors Affecting the Time to Start Postoperative Chemotherapy in Colorectal Cancer

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04885283
Enrollment
800
Registered
2021-05-13
Start date
2021-01-20
Completion date
2021-04-10
Last updated
2021-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the Time to Start Postoperative Chemotherapy

Keywords

Laparoscopy, overall survival, local recurrence, tumor, chemotherapy, colorectal cancer

Brief summary

Colorectal cancers are common tumors and have undergone a great change in the last 20 years in terms of treatment principles. Significantly improved results in local recurrence and overall survival have begun to be obtained with chemotherapy protocols given after surgery, which is the main element of the treatment system (1). It is known that postoperative chemotherapy protocols are commonly given within 6-8 weeks and this period is optimal. However, it was found that this period was prolonged in approximately 20% of these patients in the methanalysis performed (2). It has been shown that delay in applied chemotherapy causes a decrease in overall survival (3,4). The factors causing this delay have not been adequately examined in the literature. It is necessary to investigate these factors that affect the overall survival outcomes, which are the main pillars of treatment principles, and to regulate the factors that have the opportunity to improve. In this study, our aim is to investigate the perioperative (preop-perop-postop) factors affecting the duration of postoperative chemotherapy initiation in patients with colorectal cancer treated in our hospital.

Interventions

None listed

Sponsors

Inonu University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

patients who underwent colorectal resection

Exclusion criteria

patients with missing data

Design outcomes

Primary

MeasureTime frameDescription
Time to Start Postoperative Chemotherapy3 monthstime elapsed to start chemotherapy after the operation

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026