Sex or no Sex: That is the Question.

Sex or no Sex: That is the Question. Impact of Coital Sexual Intercourse on the Clinical Pregnancy Rate After Embryo Transfer.

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04880590

Enrollment

412

Registered

2021-05-11

Start date

2021-05-04

Completion date

2026-04-15

Last updated

2026-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Female, Sexual Intercourse

Brief summary

This study aims to evaluate the impact of sexual intercourse and orgasm in the 72 hrs following embryo transfer of blastocysts on the clinical pregnancy rate. An impact on sexual activity and a decrease in the frequency of intercourse has been observed in infertile couples. In couples who undergo assisted reproductive technology (ART), sexual relations have an additional component that can condition them, such as the fear of influencing the outcome of the cycle. The usual practice in ART cycles has evolved towards a preference for blastocyst-stage embryo transfer, both in fresh in vitro fertilization (IVF) cycles and in frozen embryo transfer (FET) cycles. The investigators consider it important to elucidate whether coital intercourse after embryo transfer (ET) has an impact on the clinical pregnancy rate after the transfer of blastocyst-stage embryos.

Detailed description

It is proposed to carry out an observational, prospective study, in which women with a heterosexual sexual relationship are included, who carry out an embryo transfer, in a FET cycle in the Dexeus Woman Reproduction Medicine Service and who agree to participate in the same.

Interventions

OTHERSex intercourse

A heterosexual sexual relationship

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Women with a heterosexual sexual relationship * That they carry out an embryo transfer, in a FET cycle

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Clinical pregnancy rate	6-7 weeks after transfer	Clinical pregnancy rate measured by ultrasound with the presence of a positive fetal heartbeat

Secondary

Measure	Time frame	Description
Miscarriage rate	Until 13 weeks after embryo transfer procedure	The loss of a pregnancy during the first 13 weeks of pregnancy
Live birth rate	Until 42 weeks after embryo transfer	Number of live birth after embryo transfer

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 9, 2026