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Weight Training With VR in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Effects of Weight Training With VR on Pulmonary Function, Exercise Capacity and Quality of Life in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04880486
Enrollment
22
Registered
2021-05-10
Start date
2019-09-18
Completion date
2021-08-31
Last updated
2022-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD, COPD Exacerbation, Muscle Strength, Pulmonary Function, Pulmonary Rehabilitation, Quality of Life, Readmission, Virtual Reality, Weight Training

Keywords

Acute exacerbation of chronic obstructive pulmonary disease, upper extremity weight training, virtual reality, exercise capacity, functional capacity, adherence rate of exercise

Brief summary

Using weight training with virtual reality can help after discharge patients of acute exacerbation of chronic obstructive pulmonary disease, which maintained their quality of life, and improved their exercise capacity, pulmonary function, readmission condition.

Detailed description

Chronic obstructive pulmonary disease (COPD) is a type obstructive lung disease which had become the third leading cause of deaths worldwide. The main symptoms including dyspnea, coughing, sputum production and acute exacerbation of COPD (AECOPD). The physical activity level, muscle power, exercise tolerance and quality of life (QoL) would decline rapidly when an episode of AECOPD occurred, with the worsen of the pulmonary function and activities level, the patient would get weaker and mortality rate would increase. Pulmonary rehabilitation (PR) had become a common-used clinical programs which including (but not limit to) medication, education, psychological support, nutrition consultation and exercise interventions. In PR programs, exercise had been specifically pointed out for its improvement of physical activity level and quality of life, however, the adherence rate of programs remains low due to lack of motivation and insufficient training effect. Previous interventions preferred aerobic exercise conducting in sitting position considering the long-term sedentary life style of patients. However, such an intervention demonstrated little effect on increasing muscle power of lower extremities, results in insufficient physical activity level and functional performance. Besides, the interventions are usually single and repeatedly limb movement exercise which fail to brings up interests and results in poor motivation of the patients. Literatures review has suggested the highly involvement of upper extremities which is strongly contributed to independently daily living. The implantation of virtual reality in PR program has gained attentions with its advantage of facilitate the motivation. Therefore, the study aims to conduct the muscle strength training including both upper and lower extremities with the combination of virtual reality (VR). Anticipated result expects to provide a research evidence of innovative pulmonary rehabilitation exercise intervention. The study will recruited 30 participants who will be randomly divided into control and intervention group. Control group will receive routine pulmonary rehabilitation including medication and education, the research stuff will give a brief explanation of home exercise, and weekly telemedicine to follow the exercise intensity and provide conciliation. Intervention group will receive the routine medical care. Extra weight training program targeting on upper extremities with the VR headsets will be conducted with the accompany of the research stuff. 3 times a week for 8 weeks (as a 24-times interference totally) interventions with muscle strength, exercise capacity, pulmonary function and improvement of quality of life will be assess to investigate the training effects. Expected result including the progression of muscle strength, oxygen uptake level, as well as pulmonary performance. The implantation of VR will also improve the motivation to participant, which will further alleviate the symptoms and quality of life. It can also provide some research evidence for clinical therapist to conduct an individualized exercise prescription for COPD.

Interventions

OTHEREducation

Usual pulmonary rehabilitation education and pharmacological therapies, and taught them some limbs exercise, using social application to contact and suggestion giving as supervision.

OTHERSupervision upper limb weight training exercise with VR

Participant is supervised by physical therapist to conduct upper limb weight training exercise with VR.

Sponsors

National Cheng-Kung University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
40 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* hospitalization due to acute exacerbation of chronic obstructive pulmonary disease in preceding 1-year history * age was between 40 to 85 years old

Exclusion criteria

* having a pulmonary rehabilitation in the past 1 month * comorbidities that don't suitable for pulmonary rehabilitation, such as, untreatable cardiovascular disease, sinus tachycardia (HR\>120), hypertension at rest if not adequately controlled, resting systolic blood pressure \< 90 mmHg, and exercise contraindication * advanced cancer with fatigue syndrome * can't follow the orders * physical impairment * psychological impairment

Design outcomes

Primary

MeasureTime frameDescription
Muscle Strengthbaselineusing handhold dynamometer to test 5 motions for bilateral side for 3 times.
Cardiopulmonary exercise function testbaselineusing CPET to test for the maximal exercise performance of participant

Secondary

MeasureTime frameDescription
Pulmonary function test4 times (baseline, 4 weeks, 8 weeks, 12 weeks)using spirometry to test for pulmonary function of participant FEV1/FVC in liter
Respiratory muscle force4 times (baseline, 4 weeks, 8 weeks, 12 weeks)using digital pressure Guage to test for inspiratory/expiratory muscle force of participant MIP/MEP in cmH2O
Quality of life questionnaire4 times (baseline, 4 weeks, 8 weeks, 12 weeks)using questionnaires of EuroQol-5 Dimension (EQ-5D) to test for the quality of life of participant EuroQol-5 Dimension (EQ-5D): 5 levels of health status description to measure quality of life, a higher level means a worsen outcome

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026