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TCHCCT-Zhong-Xing-Emergency-Department Ultrasound With IV Contrast in Acute Flank Pain

A Novel Technique for the Assessment of Non-traumatic Pain Diagnosis in the Emergency Department.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04877886
Enrollment
120
Registered
2021-05-07
Start date
2021-06-01
Completion date
2024-05-31
Last updated
2021-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Flank Pain

Keywords

Acute flank pain, Ultrasound, IV contrast

Brief summary

To evaluate the efficiency of ultrasound with IV contrast and compare this with the Computed Tomography in acute flank pain patient at Emergency Department.

Detailed description

Acute flank pain is a common chief complaint in emergency departments (ED), but it is a challenge for physicians in ED to accurately diagnose. It can cause variable diseases and is in many cases lethal (e.g. aortic dissection, ruptured aortic aneurysm, renal artery dissection, ruptured tumor, etc). The computed tomography scan with IV contrast is an ideal tool to diagnose due to its high sensitivity and specificity and is a golden standard examination. However, currently point-of-care ultrasound is routinely used as first-line technique. As this procedure is non-invasive and has no radiative effect, it is considered more logical, especially for those critical patients who are not able to move and perform the CT scan. Furthermore, the iodine contrast of CT scan is known as renal toxicity and should be used with caution in patient with hyperthyroidism and allergy to the contrast. The radiation of CT scan would be harmful to the pregnant patient as well. IV contrast ultrasound is a novel technique nowadays and it is widely used in diagnosing breast, liver, renal and pancreatic tumors. The ultrasound contrast using air microbubbles could enhance the scanning quality and also has high sensitivity and specificity. In ED, ultrasound with contrast now could be applied to the abdominal trauma and pediatric injury. For those patients with poor renal function, thyroid disease and pregnant women who cannot undergo IV contrast CT, IV contrast ultrasound provides a faster and safer way to evaluate patients in ED. We compared CT and ultrasound with IV contrast to determine the difference in efficiency between both examinations.

Interventions

DIAGNOSTIC_TESTUltrasound with IV contrast

To compare the efficiency over the ultrasound scan within contrast

DIAGNOSTIC_TESTCT with IV contrast

CT with IV contrast

DIAGNOSTIC_TESTUltrasound without IV contrast

Ultrasound without IV contrast

DIAGNOSTIC_TESTCT without IV contrast

CT without IV contrast

Sponsors

Taipei City Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Acute flank pain who visit ER

Exclusion criteria

* Younger than 18 years old * Known allergy to contrast

Design outcomes

Primary

MeasureTime frameDescription
The diagnostic rate of ultrasound with IV contrast in acute flank pain patientThe hospitalization of each participant, up to 28 daysEvaluate the sensitivity and specificity in ultrasound scan

Secondary

MeasureTime frameDescription
To compare the efficiency over the ultrasound and CT scan within or without contrastThe hospitalization of each participant, up to 28 dayscompared the sensitivity and specificity between CT and ultrasound scan

Countries

Taiwan

Contacts

Primary ContactTzu-Yao Hung, MD
bryansolitude@gmail.com886-979305599

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026