ERAS, Knee Osteoarthritis
Conditions
Brief summary
The study aimed to investigate the impact of enhanced recovery after surgery (ERAS) protocols on the clinical effect of total knee arthroplasty (TKA) via the midvastus approach
Detailed description
In this study, a randomized controlled study was conducted to further investigate the impact of ERAS protocols in the clinical efficacy of TKA with the midvastus approach. The ERAS protocols were adopted for the ERAS group and consisted of pure juice drinking 2 hours before the surgery, optimization of the preoperative anesthesia plan, phased use of tourniquets, and the use of tranexamic acid as well as a drug cocktail. The operative time, first postoperative walking time, first straight leg elevation time, postoperative hospitalization time, visual analogue scale score (VAS score), New York Hospital of Special Surgery knee score (HSS score), Knee Society Score (KSS score), and knee range of motion were used to assess the clinical effects in the two groups. All the included patients were followed up for 12 months.
Interventions
PROCEDUREERAS protocols for TKA
ERAS protocols for TKA
Sponsors
Nanjing First Hospital, Nanjing Medical University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
56 Years to 74 Years
Healthy volunteers
No
Inclusion criteria
* Unilateral primary knee osteoarthritis * Varus, valgus, and flexion contracture deformity of the knee joint \< 10° * The range of motion of the knee joint was \> 80° * Body mass index (BMI) \< 30 * No previous history of knee surgery on the affected side .Agreed to participate in the trial.
Exclusion criteria
* Rheumatoid arthritis * Extra-knee deformity * Simultaneous bilateral knee arthroplasty * Severe dysfunction of the liver, kidney, and blood system * Severe cardiovascular diseases * Gastrointestinal ulcer .Other medical conditions like nausea, vomiting, snoring, and allergy to related analgesic drugs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the postoperative hospitalization time | 12 months | the postoperative hospitalization time |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| first straight leg elevation time | 1 day | first straight leg elevation time |
| the operative time | 2 hours | the operative time |
| first postoperative walking time | 1 day | first postoperative walking time |
| visual analogue scale score (VAS score) | 12 months | VAS score (0-10 scores) is for pain: 0 represent no pain, 1-3 represent mild pain, 4-6 represent moderate pain, 7-10 represent severe pain. |
| Knee Society Score (KSS score) | 12 months | KSS score (0-100 scores) is for knee function: 85-100 represent excellent, 70-84 represent good, 60-69 represent fair, 0-59 represent bad. |
| knee range of motion | 12 months | knee range of motion |
| New York Hospital of Special Surgery knee score (HSS score) | 12 months | HSS score (0-100 scores) is for knee function: 85-100 represent excellent, 70-84 represent good, 60-69 represent fair, 0-59 represent bad. |
Countries
China
Outcome results
None listed