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Establishment of Online Registration Platform for Unruptured Intracranial Aneurysms Based on 100 Regional Medical Centers in China and Population Follow-up Study

Establishment of Online Registration Platform for Unruptured Intracranial Aneurysms Based on 100 Regional Medical Centers in China and Population Follow-up Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04872842
Enrollment
1000
Registered
2021-05-05
Start date
2021-09-01
Completion date
2022-05-01
Last updated
2022-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial Aneurysm

Keywords

intracranial aneurysm, online registration platform, artificial intelligence, multidimensional model

Brief summary

In this study, 20 regional neurosurgery centers across the country will be included, and the study cohort will be constructed on the basis of the IARP-CP cohort.The artificial intelligence platform was used to analyze the clinical, morphological, hemodynamics, aneurysm wall characteristics and other factors of unruptured aneurysms, as well as the relationship between these factors and the risk of aneurysm instability, seek the potential risk factors, and finally establish a multi-dimensional prediction model of rupture risk of intracranial aneurysms.

Interventions

This study is an observational study without any intervention

Sponsors

Beijing Hospital
CollaboratorOTHER_GOV
Peking University Third Hospital
CollaboratorOTHER
Beijing Sanbo Brain Hospital
CollaboratorOTHER
Beijing Chao Yang Hospital
CollaboratorOTHER
Binzhou Renmin Hospital
CollaboratorUNKNOWN
Fujian Medical University Union Hospital
CollaboratorOTHER
First Affiliated Hospital of Fujian Medical University
CollaboratorOTHER
Guangzhou Red Cross Hospital
CollaboratorOTHER
The First Affiliated Hospital of Haerbin Medical University
CollaboratorUNKNOWN
The Affiliated Hospital of Qingdao University
CollaboratorOTHER
Shanxi Provincial People's Hospital
CollaboratorOTHER_GOV
Beijing Tsinghua Changgeng Hospital
CollaboratorOTHER
RenJi Hospital
CollaboratorOTHER
Sichuan Provincial People's Hospital
CollaboratorOTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
CollaboratorOTHER
The Affiliated Hospital of Kunming Medical University
CollaboratorUNKNOWN
Beijing Unimed Technology Company
CollaboratorUNKNOWN
Beijing Tiantan Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years

Inclusion criteria

1. 18-75 years old; 2. At least one unruptured intracranial aneurysm was found by CTA; 3. No relevant symptoms, receiving non-operative and conservative observation treatment; 4. Signing the informed consent.

Exclusion criteria

1. Other cerebrovascular structural lesions (such as cerebrovascular malformation and arteriovenous fistula) or craniocerebral tumors; 2. Fusiform or dissecting aneurysms; 3. Traumatic, mycotic and atrial myxoma associated aneurysms; 4. Suffering from systemic connective tissue diseases, such as polycystic kidney disease; 5. Expectant survival of no more than 3 years due to other diseases or poor general conditions; 6. Patients refuse to follow up or cannot communicate with them due to mental diseases; 7. Pregnant women or participating in other aneurysm related studies.

Design outcomes

Primary

MeasureTime frame
Aneurysm rupture2 years

Secondary

MeasureTime frame
Aneurysm growth2 years

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026