Apical Root Resorption
Conditions
Brief summary
The goal of this prospective clinical trial is to evaluate the possible superiority of a treatment compared to the gold standard of reference in Orthodontics.
Detailed description
Apical external root resorption is defined as the loss of dental hard tissues such as dentine, cement and alveolar bone. This is considered an irrevocable effect associated to different factors, among which dental movement during orthodontic treatment is related. This study suggest to compare root resorption after the use of two different types of alignment and levelling arches in orthodontics. Consecutive patients randomly chosen will be analysed after going through one of the two arches sequences: 1. Gold standard group: using arches that provide the same amount of force in all sections . 3M United® nickel-titanium arches (0.012, 0.014, 0.016 x 0.016, 0.020 x 0.020, 0.018 x 0.025 y 0.019 x 0.025) 2. Intervention group: using some arches that provide individual sectional forces for each dental group (incisors, premolars and molars). 3M United® nickel-titanium 0.012 and 0.014 arches and BioForce PLUS® arches (0.016 x 0.016, 0.020 x 0.020, 0.018 x 0.025 y 0.019 x 0.025). All patients will be treated with multi-braces fixed appliances (0.022 technique and VictoryTM brackets). Root resorption will be compared through CBCT (Cone Beam Computed Tomography) images made before the beginning of treatment (T0), after 8-9 months of the beginning of treatment (T1) and at the end of treatment (T2). Root resorption will be measured by the root volume and surface root morphology in each of the times scheduled.
Interventions
PROCEDUREMaxillary and mandibular Cone Beam Computed Tomography record
A Cone Beam Computed Tomography image of each patient of each group at three different moments of the study (baseline/T0, 8-9 months of treatment/T1 and end of treatment/T2)
Sponsors
Universidad Complutense de Madrid
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Intervention model description
Randomized clinical trial of two parallel arms, that analysed the possible superiority of one treatment compared to the gold standard of reference
Eligibility
Sex/Gender
ALL
Age
12 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
Study Population: patients undergoing orthodontic treatment in Orthodontic Department at Dental School of Universidad Complutense de Madrid. Inclusion Criteria: 1. Completed permanent dentition (third molars are excluded) 2. Completed root formation 3. Need of orthodontic treatment
Exclusion criteria
1. Tooth agenesis in the anterior region (incisors) 2. Included or ankylosed teeth in the anterior region (incisors) 3. Periodontal pocket \>3 mm in any anterior teeth (incisors) 4. Need of a combined surgical and orthodontic treatment 5. Root resorptions observed at the initial CBCT (in more than 3 teeth) 6. Delay of the treatment due to a external reason or complication during treatment 7. Systemic disease or cranio-facial malformation 8. Tooth fracture or restoration in the anterior region (incisors) at the beginning of treatment 9. Problems from roots such as lacerated root, trauma or fractures during treatment 10 Severe occlusal attrition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference of volume of the apical portion of the root | Baseline/beginning treatment (T0), 34 weeks after beginning treatment (T1) and through treatment completion (T2) | Measure of the 5 more apical mm3 of the root at each moment of treatment (T0, T1 and T2) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Root volumen | Baseline/beginning treatment (T0), 34 weeks after beginning treatment (T1) and through treatment completion (T2) | Measure of the total volume of each root at momento of treatment (T0, T1 and T2) |
| Root surface area | Baseline/beginning treatment (T0), 34 weeks after beginning treatment (T1) and through treatment completion (T2) | Measure of the outer surface of the root dentine at momento of treatment (T0, T1 and T2) |
Countries
Spain
Outcome results
None listed