Using Smart Phone Technology to Support PrEP Uptake and Adherence

Using Smart Phone Technology to Support PrEP Uptake and Adherence in Virginia - Pilot Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04868383

Acronym

prep'd

Enrollment

Registered

2021-04-30

Start date

2019-01-01

Completion date

2020-12-30

Last updated

2021-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adherence, Medication, HIV Prevention, PrEP

Keywords

HIV, Prevention, Adherence, Uptake

Brief summary

This is a single arm pilot study of a new smartphone app to support adherence to PrEP medication for HIV prevention in public clinics in Virginia.

Detailed description

Testing the impact of a smart phone application's impact on PrEP uptake and adherence. The app features daily medication reminders, daily mood and stress evaluations, a community message board for social support, and patient-provider secure, HIPAA compliant private messaging between patients and clinic providers. Participants will be recruited from VDH clinics. We will evaluate the adherence and uptake rates of PrEP among study participants. Usage data will be collected from the application, and from participant surveys at 30 day, 3 month, and 6 month study timepoints. Surveys will include questionnaires on medication adherence, empathy of providers, experiences with the app, stigma and disclosure attitudes, and social support, along with mental health screening. The study will be analyzed as a prospective one arm study by comparing baseline to 3M and 6M surveys, along with examining and characterizing app usage across time.

Interventions

BEHAVIORALUse of smart phone technology to support medication adherence and uptake

Use of smart phone technology to support medication adherence and uptake

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 years of age or older * one or considering being on PrEP for HIV prevention * Patient at a VDH or VDH funded clinic * ability to read at a 5th grade reading level

Exclusion criteria

* HIV positive individuals * Persons under the age of 18

Design outcomes

Primary

Measure	Time frame	Description
Adherence	6 months	Overall percentage of PrEP medication adherence

Secondary

Measure	Time frame	Description
Usability	6 months	How usable is the app to both patient participants and provider participants

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026