Adolescent Idiopathic Scoliosis
Conditions
Brief summary
The aims of this pilot study are to determine the metabolic demand and exercise intensity level of E-Fit exercise intervention by evaluating the cardiovascular responses in AIS girls and whether the cardiovascular responses for AIS girls performing E-Fit will behave in the same way as compared to healthy controls. We hypothesise that 1) the metabolic demand and exercise intensity of E-Fit exercise intervention is equivalent to moderate-to-vigorous level; and 2) AIS girls have different cardiovascular responses as compared to healthy controls
Detailed description
AIS girls and age- and gender-matched healthy controls will perform the E-Fit exercise intervention for two trials and gas exchange parameters including oxygen consumption (VO2) and carbon dioxide production (VCO2) will be taken continuously during the exercise. Comparison of VO2 and VCO2 between AIS and healthy controls when performing E-Fit exercise will be made.
Interventions
BEHAVIORALExercise
Two trials of 7-min High Intensity Interval Training (HIIT) with 12 different exercises. Each exercise lasts for 30 seconds continuously with 10 seconds rest interval.
Sponsors
Chinese University of Hong Kong
Tung Wah College
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
10 Years to 16 Years
Healthy volunteers
Yes
Inclusion criteria
* Cobb angle greater or equal to 15 degree * Cleared for physical activity by doctor
Exclusion criteria
* Cobb angle greater or equal to 40 degree, or * Scoliosis with any known etiology, scoliosis with skeletal dysplasia, know endocrine and connective tissue abnormalities, or * Known heart condition or other diseases that could affect the safety of exercise, or * Eating disorders or GI malabsorption disorders, or * Currently taking medication that affects bone or muscle metabolism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory gas measurement | Day 1 | Breath-by-breath measurement of cardiorespiratory and gas exchange parameters to analyse oxygen consumption (VO2 in ml/min) and carbon dioxide production (VCO2 in ml/min). |
| Blood Pressure | Day 1 | Blood pressure (mmHg) will be measured using an electronic sphygmomanometer. |
| Heart rate | Day 1 | Heart rate (bpm) will be measured using a fingertip oximeter. |
| Oximetry | Day 1 | Peripheral capillary oxygen saturation (%) will be measured using a fingertip oximeter. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sitting height | Day 1 | Sitting height (cm) will be measured with standard stadiometry techniques. |
| Maturity assessment | Day 1 | Sexual maturity using Tanner Scale and onset of menarche will be measured. |
| Body Composition | Day 1 | Percentage body fat (%), body weight (kg), lean muscle mass (kg) will be assessed using Bioelectric Impedance Analysis. |
| Arm Span | Day 1 | Arm span (cm) will be measured with standard stadiometry techniques. |
| Modified Baecke Questionnaire | Day 1 | Habitual physical activity level will be assessed by self-administered questionnaire. |
| Physical Activity Rating Questionnaire for Children and Youth (PARCY) | Day 1 | Physical activity level and intensity will be assessed by self-administered questionnaire. |
| Body height | Day 1 | Body height (cm) will be measured with standard stadiometry techniques. |
Countries
Hong Kong
Outcome results
None listed