The Cholelithiasis in Adults With Short Bowel Syndrome

Prevalence, Risk Factors, and Complications of Cholelithiasis in Adults With Short Bowel Syndrome

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04867538

Enrollment

345

Registered

2021-04-30

Start date

2010-01-01

Completion date

2020-12-31

Last updated

2021-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Short Bowel Syndrome

Keywords

Short bowel syndrome, Cholelithiasis, Prevalence, Risk factors

Brief summary

Short-term studies have shown that patients with short bowel syndrome (SBS) often develop cholestasis or cholelithiasis. In this retrospective cohort study, we aimed to define the incidence, risk factors, and clinical consequences of cholelithiasis in adults with SBS over an extended time period.

Detailed description

However, only limited data are available regarding cholelithiasis in patients with SBS. The prevalence of cholelithiasis in patients with SBS has been reported only in two studies. Furthermore, few studies have focused on identifying the risk factors for cholelithiasis in patients with SBS. Considering the marked improvements in medical care and nutrition support during the last 2 decades, the current incidence and risk factors for cholelithiasis in patients with SBS are unknown. The aim of the current study was to provide comprehensive, longitudinal, and long-term data on the incidence of symptomatic and asymptomatic cholelithiasis in a cohort of patients with SBS, in order to identify the prevalence, risk factors, and clinical consequences of cholelithiasis in patients with SBS to aid in the development of protective interventions.

Interventions

OTHERno intervention

No intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

All eligible adults diagnosed with SBS

Exclusion criteria

age \<18 years; history of cholelithiasis before SBS diagnosis; cholecystectomy; biliary tract obstruction or no abdominal imaging (CT, MRI, or ultrasound) after SBS diagnosis.

Design outcomes

Primary

Measure	Time frame	Description
the incidence of cholelithiasis in patients with SBS	2010/1/1-2019/12/31	the incidence of symptomatic and asymptomatic cholelithiasis in a cohort of patients with SBS
risk factors	2010/1/1-2019/12/31	the risk factors of cholelithiasis in patients with SBS
complications	2010/1/1-2019/12/31	the clinical consequences of cholelithiasis in patients with SBS

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 13, 2026