Prediction of Chronic Postsurgical Pain in Adults

Prediction Model Development for Chronic Postsurgical Pain in Adults

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04866147

Enrollment

1522

Registered

2021-04-29

Start date

2021-05-25

Completion date

2023-08-15

Last updated

2023-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Post Operative Pain, Chronic Postsurgical Pain

Brief summary

This research will be a prospective single-centre observational cohort study in Denmark spanning approximately one year. The objective of this study is to develop a clinically applicable and generalizable prediction model for postsurgical pain in adults.

Interventions

PROCEDURECardiothoracic surgery

Cardiac & large intrathoracic vessels, respiratory, thoracic, mediastinal & diaphragmatic procedures

PROCEDUREBreast surgery

Breast resections & mastectomies

PROCEDUREGastrointestinal surgery

Digestive & spleen

PROCEDUREGenitourinary surgery

Urinary tract, genital & retroperitoneal tissue

PROCEDUREOrthopaedic surgery

Back & neck, shoulder & upper arm, hip & thigh, knees & lower leg

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Consenting Danish-speaking adults aged 18 years and older * Patients who undergo common inpatient or outpatient surgical procedures

Exclusion criteria

* Patients with cognitive impairment * Patients who refuse or unable to provide informed consent * Patients who undergo re-operation within 3 months of their initial surgery

Design outcomes

Primary

Measure	Time frame	Description
Chronic post surgical pain	3 months post surgery	Pain related to the surgical procedure measured as average pain intensity on rest or movement using 11-point numeric rating scale (NRS; 0-10) where 0=no pain and 10=worst pain imaginable and/or average pain interference using 11-point NRS among any one of seven short-form Brief Pain Inventory items (general activity, mood, walking ability, normal work (including housework), relations with other people, sleep, enjoyment of life) in the past one week, where 0=pain does not interfere and 10=pain completely interferes.

Secondary

Measure	Time frame	Description
Acute post surgical pain	First 3 hours after surgery	Acute post surgical pain intensity in the first 3 hours after surgery measured as pain at rest using 11-point numeric rating scale (NRS; 0-10) where 0=no pain and 10=worst pain imaginable.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 13, 2026