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Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04865614
Acronym
COMPETENT
Enrollment
57
Registered
2021-04-29
Start date
2019-04-01
Completion date
2020-12-01
Last updated
2021-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Hypotension Drug-Induced

Brief summary

The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase. This retrospective cohort study aims to find out if the choice of the induction agent has a major impact on blood pressure and the use of catecholamines during the induction and the interventional procedure in patients undergoing interventional mitral valve repair.

Interventions

DRUGEtomidate

Use of etomidate

DRUGSevoflurane

Use of sevoflurane

Sponsors

University Hospital, Essen
CollaboratorOTHER
Heidelberg University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Patients undergoing elective interventional mitral valve repair * Sevoflurane or etomidate have been used for induction of anesthesia

Exclusion criteria

* Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Post-induction hypotensionFirst 20 minutes after induction of anaesthesiaHypotension in the first 20 minutes after induction of anesthesia

Secondary

MeasureTime frameDescription
Use of catecholamines after induction during the first 20 minutes after inductionafter inductionFirst 20 minutes after inductionUse of catecholamines during the first 20 minutes after induction of anaesthesia
Use of catecholaminesLength of procedure (Approximately 60 to 90 minutes in average)Use of catecholamines during the procedure

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026