Infection, Inflammation, Mediastinitis, Neck Abscess
Conditions
Brief summary
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections.
Detailed description
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections. The study enrolled patients admitted to the Emergency Center of Vojvodina with the diagnosis of multispace DNI with or without DNM either as the primary diagnosis or with discharged diagnosis after surgical treatment during 7-years period. The data were obtained from patient medical records.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* patients admitted to the hospital due to deep neck infection affecting two or more spaces with or without descending necrotizing medioastinitis * complete diagnosis and treatment data available from medical charts
Exclusion criteria
* incomplete medical data * infection confined to one deep neck space * patients treated under local anesthesia * patients with superficial skin infections * iatrogenic infections * infected tumors
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of mediastinitis | Within 6 hours of admission | Neck and chest computed tomography (CT) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Microbiological findings in DNI and DNM | Within 1 week of admission | Prevalence of microorganisms in mediastinitis |
| Average number of hospital days | Through study completion, an average of one month | Comparison of average number of hospital days in DNI and DNM |
| Incidence of complications | Within 30 days from admission | Complications among DNI and DNI+DNM groups |
| Number of infected deep neck spaces | Within 6 hours of admission | Neck and chest computed tomography (CT) |