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Effect of Intake of Hydrolyzed Krill Protein Isolate on Plasma Amino Acid Profile

Effect of Intake of Hydrolyzed Krill Protein Isolate, Whey Protein Isolate and Soy Protein Isolate on Plasma Amino Acid Profile

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04864769
Acronym
KRILL
Enrollment
10
Registered
2021-04-29
Start date
2019-11-01
Completion date
2021-01-01
Last updated
2021-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human Nutrition

Keywords

Protein, Amino Acids, Krill, Whey, Soy, Satiety, Insulin

Brief summary

Purpose: To examine the absorption of three different protein sources: hydrolyzed krill protein isolate, whey protein isolate, and soy protein isolate.

Detailed description

Design and Method: Randomized, controlled, double-blind cross-study, in which 12 healthy adult young men in randomized order ingest 35 g of protein of crude protein from one of the three protein sources or water on four different experimental days. Before and up to three hours after ingestion of the test beverage, blood samples are collected for 8 time points during each experimental day.

Interventions

DIETARY_SUPPLEMENTKrill protein hydrolysate

Ingestion of 35 g Krill protein hydrolysate

DIETARY_SUPPLEMENTSoy protein isolate

Ingestion of 35 g Soy protein isolate

DIETARY_SUPPLEMENTWhey protein isolate

Ingestion of 35 g Whey protein isolate

DIETARY_SUPPLEMENTWater

Ingestion of water (control)

Sponsors

Aker BioMarine Human Ingredients AS
CollaboratorINDUSTRY
Mette Hansen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Intervention model description

Design and Method: Randomized, controlled, double-blind cross-study, in which 12 healthy adult young men in randomized order ingest 35 g of protein of crude protein from one of the three protein sources or water on four different experimental days. Before and up to three hours after ingestion of the test beverage, blood samples are collected for 8 time points during each experimental day.

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* men * 18-30 years

Exclusion criteria

* smoking, * medication, * health issues conflicting with the experimental trial

Design outcomes

Primary

MeasureTime frameDescription
Amino acids concentrations10 minutes prior to supplement up to 180 minutes after supplementMeasurement of changes in amino acids concentrations in the blood

Secondary

MeasureTime frameDescription
Visual Analogue Scale (VAS)10 minutes prior to supplement up to 180 minutes after supplementMeasurements of changes in Hunger and satiety using 100 mm Visual Analogue Scores
Insulin10 minutes prior to supplement up to 180 minutes after supplementChanges in serum insulin

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026