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Artificial Intelligence in Image Recognition of Pouchoscopies in Patients With Restorative Proctocolectomy

Artificial Intelligence in Image Recognition of Pouchoscopies in Patients With Restorative Proctocolectomy

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04864587
Acronym
PouchVision
Enrollment
500
Registered
2021-04-29
Start date
2021-06-01
Completion date
2023-06-01
Last updated
2023-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pouches, Ileoanal

Brief summary

The application of artificial intelligence in pouchoscopy of patients with restorative proctocolectomy might improve the diagnosis of pouchitis and neoplasms. The aim of this pilot study is to develop a convolutional neural network algorithm for pouchoscopy

Detailed description

Restorative proctocolectomy is the standard procedure for treatment of refractory severe colitis in inflammatory bowel disease as well as the standard procedure for carcinoma preventive treatment of patients with inflammatory bowel disease with colonic neoplasia and patients with familial adenomatous polyposis coli (FAP). Pouchoscopy can be used to monitor the success of therapy and to detect complications such as pouchitis or neoplasia. Artificial Intelligence assisted image recognition programs can support the examiner in finding a diagnosis and train physicians in training, objectify endoscopic findings in the context of studies and might make biopsies unnecessary, thus saving costs. The application of Artificial Intelligence in pouchoscopy has not been demonstrated to date. The aim of this study is to develop, an image recognition algorithm that reliably detects the different graduations of pouch inflammation. This requires training and fine-tuning of the image recognition program PiTorch using the largest possible amount of image data, which will be recruited from the image databases of the UMM and the Theresienkrankenhaus Mannheim. A test run for statistical evaluation will be performed on an independent cohort.

Interventions

DIAGNOSTIC_TESTArtificial intelligence used for image recognition in pouchoscopy

The aim of this study is to develop an image recognition algorithm that reliably detects the different graduations of pouch inflammation and neoplasms in the pouch

Sponsors

Universitätsmedizin Mannheim
CollaboratorOTHER
Theresienkrankenhaus und St. Hedwig-Klinik GmbH
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• All patients aged ≥ 18 years with inflammatory bowel disease and status after restorative proctocolectomy with ileoanal pouch who had received a pouchoscopy

Exclusion criteria

• Very poor endoscopic image quality

Design outcomes

Primary

MeasureTime frameDescription
AI versus endoscopistImmediately after application of AI algorithm or after assessment of the endoscopic image by the endoscopistDetection of pouchitis by AI versus assessment by endoscopist in pouchoscopy
AI versus pathologistImmediately after application of AI algorithm or after assessment of the microscopic image of the pouch biopsy by the pathologistDetection of pouchitis by AI versus pathologist in pouchoscopy

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 19, 2026