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Effect of Osteopathic Techiniques on Intraocular Pressure

Effect of Osteopathic Techiniques on Intraocular Pressure: a Randomized Double-blind Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04863209
Enrollment
7
Registered
2021-04-28
Start date
2021-09-28
Completion date
2021-11-19
Last updated
2021-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Pressure, Osteopathic Manipulative Treatment

Keywords

intraocular pressure, sphenopalatine ganglion, superior cervical ganglion, aqueous humour

Brief summary

The purpose of this study is to assess the effects osteopathic techniques at the upper cervical vertebrae or at the sphenopalatine ganglia on the intraocular pressure.

Detailed description

The 7 volunteers will be randomized into 3 groups and there will be an experimental group 1 that will receive a technique of manipulation of the upper cervical, an experimental group 2 that will receive a technique of manipulation of the sphenopalatine ganglion and a control group that will not receive any intervention. Each volunteer will participate in the 3 groups. There will be 4 assessments, one before the procedure and one just after each procedure, including the control.

Interventions

The patient will receive an upper cervical manipulation as described in the Experimental Group 1.

OTHERSphenopalatine ganglion manipulation

The patient will receive a sphenopalatine ganglion as described in the Experimental Group 2.

Sponsors

Federal University of São Paulo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Intraocular pressure below 21mmHg

Exclusion criteria

* Positive Klein test * Use of medications that affect the circulatory system in up to one month before the procedures; * Caffeine use 24 hours before procedures; * Presence of ophthalmic diseases; * History of hypertension or diabetes; * Blindness; * Tumor in the head; * Skull or cervical fractures that occurred less than 6 months ago.

Design outcomes

Primary

MeasureTime frameDescription
Change of the intraocular pressure after upper cervical manipulationImmediately after the intervention and 30 minutes after the interventionAfter this manipulation, it is expected that there will be a sympathetic response increasing the intraocular pressure.
Change of the intraocular pressure after sphenopalatine ganglion manipulationImmediately after the intervention and 30 minutes after the interventionAfter this manipulation, it is expected that there will be a parasympathetic response decreasing the intraocular pressure.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026