Effect of Interval Training on Arterial Stiffness in Women With Hypertension

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04862754

Enrollment

Registered

2021-04-28

Start date

2021-01-25

Completion date

2021-04-15

Last updated

2022-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arterial Stiffness

Brief summary

this study is aiming to assess the chronic effect of the interval training program on arterial stiffness in women with hypertension

Interventions

OTHERinterval training exercise

interval training exercise

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

40 Years to 60 Years

Healthy volunteers

Inclusion criteria

* physically inactive * BMI 30-40 * Stage 1 and 2 hypertension * Elevated BP as systolic BP ≥130 mm Hg and/or diastolic BP ≥85 mm Hg measured at the brachial artery.

Exclusion criteria

* Medications known to affect weight or appetite * Any disease associated with exercise intolerance. * Women were taking hormone replacement therapy

Design outcomes

Primary

Measure	Time frame	Description
Central arterial stiffness measurements (Pulse Wave Velocity [PWV], augmentation index )	two months	Pulse wave analysis (PWA) of the women in the two groups: pre and post treatment for pulse wave velocity (PWV) and augmentation index(AIx) Pulse Wave Velocity \[PWV\], augmentation index (AIx @75HR) and resting heart rate were measured using analysis equipment which called Non-invasive blood pressure measurement system using Mobil-O-Graph 24h PWA with Hypertension Management Software Client Server (HMS-CS 4.3). PWA was performed using an oscillometric Mobil-O-Graph R 24 h PWA Monitor device (I.E.M GmbH, Germany) with integrated ARCSolver® software

Secondary

Measure	Time frame	Description
blood lipid profile	two months	blood analysis will be used to measure lipid profile (high and low-density lipoprotein, cholesterol, triglyceride)
interleukin 6	two months	blood analysis will be used to measure interleukin 6
blood pressure (systolic and diastolic)	two months	resting Blood pressure was monitored from the right arm using an automated digital electronic BP monitor (Omron digital BP monitor, Model 11 EM 403c; Tokyo Japan).

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026