Acute ST-segment Elevation Myocardial Infarction, Distal Radial Artery Approach, Radial Artery Occlusion
Conditions
Brief summary
The transradial access (TRA) is currently the preferred approach for percutaneous coronary intervention (PCI). However, in patients with ACUTE ST-segment elevation myocardial infarction (STEMI) after emergency PCI, the high incidence of THE radial artery RAO limits the future choice of the radial artery for percutaneous intervention. The literature reported that distal transradial access (dTRA) significantly reduced RAO after elective PCI, but the application of dTRA in emergency PCI in STEMI has not been reported. We have completed 126 cases of dTRA undergoing emergency PCI after STEMI, which has been preliminarily confirmed to be safe and effective. A single-center, open, prospective, randomized controlled study is planned to compare the use of dTRA and TRA in emergency PCI in STEMI patients. The primary endpoint was the INCIDENCE of RAO within 24 hours after surgery. This clinical study verified that dTRA compared with TRA could reduce the RAO incidence of STEMI patients after emergency PCI. The project will explore a new artery approach to reduce RAO, and provide a basis for the selection of artery approach in STEMI emergency PCI patients.
Interventions
PROCEDUREArterial access
Arterial access for primary percutaneous coronary intervention in STEMI patients
Sponsors
Shenzhen People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of STEMI * To undergo emergency PCI treatment * Palpable pulsation of the radial artery and distal radial artery
Exclusion criteria
* Arteriovenous fistula of radial artery and cephalic vein has been performed with regular hemodialysis * Suspicious left main block of electrocardiogram * Had used the radial artery percutaneous interventional treatment before * Cardiogenic shock
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The RAO incidence during hospitalization | 7 days | The incidence of radial artery occlusion during hospitalization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Puncture time | During the intervention | Puncture time |
| Compression time | 4-24 hours | Compression time |
| Puncture success rate | During the intervention | Puncture success rate |
| Incidence of hematoma, finger numbness or pain during hospitalization | 7days | Incidence of hematoma, finger numbness or pain during hospitalization |
| Incidence of RAO at 1 and 6 months after surgery | 1 and 6 months | Incidence of RAO at 1 and 6 months after surgery |
Countries
China
Contacts
Primary ContactXin Sun, MD
Outcome results
None listed