Post COVID19 Functional and Cognitive Assessments

Vpliv COVID19 na Izgubo Funkcionalnih zmožnosti Pacientov po zaključenem bolnišničnem Zdravljenju The Effect of COVID19 on the Loss of Functional Capacity of Patients After Hospitalization

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04860206

Acronym

PostCovidZRS

Enrollment

Registered

2021-04-26

Start date

2021-01-05

Completion date

2021-09-30

Last updated

2022-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Decline, Covid19, Respiratory Disease, Walking, Difficulty

Keywords

COVID19, functional outcomes, respiratory function

Brief summary

The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment. Specifically, the research will focus on examining changes in musculoskeletal, cardiovascular, and respiratory function, as well as motor control. In addition, we aim to evaluate rehabilitation treatments after recovery from COVID -19 and consider additional preventive measures based on previous experience.

Detailed description

The combination of such a severe respiratory disease as COVID -19 with motor inactivity could have very serious consequences for a person's general health even after COVID -19 symptoms have subsided. To date, the effects of COVID -19 on individual muscle status have not been extensively studied. Therefore, the main objective of this study will be to evaluate the muscle status of patients after COVID -19. In addition, we will be interested in longitudinal monitoring of individuals' rehabilitation, where they will receive instructions based on measured outcomes at hospital discharge. We will also be interested in considering additional preventive measures for future patients based on previous experience of infected and hospitalized COVID -19 patients.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Inclusion criteria

* Completed hospital treatment after a positive COVID-19 test * Signed written consent

Exclusion criteria

* Still testing positive for COVID -19 at discharge. * Severe musculoskeletal injuries (e.g., disability). * Inability to follow instructions when performing the test.

Design outcomes

Primary

Measure	Time frame	Description
Timed up and go test (TUG)	Change in time on TUG between both assessment points (pre- to 2 months post-measurement)	Functional performance of the patients from sitting to standing, walking and turning
Pulse wave velocity (PWV)	Change in PWV between both assessment points (pre- to 2 months post-measurement)	Measuring endothelium function in supine
Spirometry	Change in FVC (%) between both assessment points (pre- to 2 months post-measurement)	Measurement of lung function, specifically the forced vital capacity (FVC)

Secondary

Measure	Time frame	Description
Walking velocity	Change in gait velocity between both assessment points (pre- to 2 months post-measurement)	measurement of gait velocity on the 4m path.
Trail making test B	Change in time to solve the TMT B test between both assessment points (pre- to 2 months post-measurement)	Measurement of executive control using the TMT B test

Countries

Slovenia

Outcome results